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Meningococcal infections

Meningococcal infections
Meningococcal infections
Background
The gram-negative diplococcus Neisseria meningitides is a major infectious cause of childhood death in developed countries. The mortality rate remains around 10%; however, in some specialist centers, it has decreased to less than 5%.1

Only meningitis is present in 30-50% of cases of invasive meningococcal disease, whereas 7-10% of cases have only features of septicemia, and 40% have meningitis with septicemia. The clinical difference between septicemia and meningitis is important because patients who present with shock are treated differently than patients who present primarily with increased intracranial pressure (ICP).

meningococcal infections, meningitis, infectious purpura fulminans, meningococcal meningitis, meningococcal septicemia, meningococcemia, neisseria meningitides, invasive meningococcal disease, increased intracranial pressure, hypovolemia, pulmonary edema, intravascular thrombosis, purpura fulminans, varicella infection, hypokalemia, hypocalcemia, hypomagnesemia, hypophosphatemia, acidosis, hypoxia, hypoglycemia, obstructive hydrocephalus, sensorineural deafness, tachycardia, tachypnea, hypotension, maculopapular rash, neck stiffness, photophobia, bradycardia, treatment, diagnosis
Faust, Saul N.
f97df780-9f9b-418e-b349-7adf63e150c1
Cathie, Katrina
4b772af2-4b34-45d4-866a-fb934376e1cd
Levin, Michael
2be78359-2a08-4885-a83c-4f7a6d1de986
Faust, Saul N.
f97df780-9f9b-418e-b349-7adf63e150c1
Cathie, Katrina
4b772af2-4b34-45d4-866a-fb934376e1cd
Levin, Michael
2be78359-2a08-4885-a83c-4f7a6d1de986

Faust, Saul N., Cathie, Katrina and Levin, Michael (2009) Meningococcal infections. In, Paediatric textbook at emedicine.com.

Record type: Book Section

Abstract

Background
The gram-negative diplococcus Neisseria meningitides is a major infectious cause of childhood death in developed countries. The mortality rate remains around 10%; however, in some specialist centers, it has decreased to less than 5%.1

Only meningitis is present in 30-50% of cases of invasive meningococcal disease, whereas 7-10% of cases have only features of septicemia, and 40% have meningitis with septicemia. The clinical difference between septicemia and meningitis is important because patients who present with shock are treated differently than patients who present primarily with increased intracranial pressure (ICP).

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More information

Published date: 11 September 2009
Keywords: meningococcal infections, meningitis, infectious purpura fulminans, meningococcal meningitis, meningococcal septicemia, meningococcemia, neisseria meningitides, invasive meningococcal disease, increased intracranial pressure, hypovolemia, pulmonary edema, intravascular thrombosis, purpura fulminans, varicella infection, hypokalemia, hypocalcemia, hypomagnesemia, hypophosphatemia, acidosis, hypoxia, hypoglycemia, obstructive hydrocephalus, sensorineural deafness, tachycardia, tachypnea, hypotension, maculopapular rash, neck stiffness, photophobia, bradycardia, treatment, diagnosis

Identifiers

Local EPrints ID: 144629
URI: http://eprints.soton.ac.uk/id/eprint/144629
PURE UUID: 9868f8ff-4442-417e-b856-53b9e94c8ada
ORCID for Saul N. Faust: ORCID iD orcid.org/0000-0003-3410-7642

Catalogue record

Date deposited: 14 Apr 2010 15:45
Last modified: 11 Dec 2021 04:09

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Contributors

Author: Saul N. Faust ORCID iD
Author: Katrina Cathie
Author: Michael Levin

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