The University of Southampton
University of Southampton Institutional Repository

The use of pencil lead as a matrix and calibrant for matrix-assisted laser desorption/ionisation

The use of pencil lead as a matrix and calibrant for matrix-assisted laser desorption/ionisation
The use of pencil lead as a matrix and calibrant for matrix-assisted laser desorption/ionisation
Pencil lead is shown to be an effective matrix and calibrant in matrix-assisted laser desorption/ ionisation (MALDI) mass spectrometry. Various groups of analytes, including peptides, polymers and actinide metals, can be readily ionised using MALDI when deposited onto a pencil lead matrix. The matrix is seen to have advantages in sample preparation relating to its hydrophobic properties and almost complete suppression of the matrix during analysis. Using pencil lead as a matrix is a quick and convenient method of qualitative analysis and has been shown to be quantitative for the isotope ratio analysis of actinide metals
0951-4198
1053-1060
Black, Claudie
3ec4f0fa-5de9-43c3-abee-dfe2c050096f
Poile, Chris
6fa3f201-ba05-40f5-8afd-60c1e48fc1f4
Langley, John
7ac80d61-b91d-4261-ad17-255f94ea21ea
Herniman, Julie
530b1a36-1386-4602-8df7-defa6eb3512b
Black, Claudie
3ec4f0fa-5de9-43c3-abee-dfe2c050096f
Poile, Chris
6fa3f201-ba05-40f5-8afd-60c1e48fc1f4
Langley, John
7ac80d61-b91d-4261-ad17-255f94ea21ea
Herniman, Julie
530b1a36-1386-4602-8df7-defa6eb3512b

Black, Claudie, Poile, Chris, Langley, John and Herniman, Julie (2006) The use of pencil lead as a matrix and calibrant for matrix-assisted laser desorption/ionisation. Rapid Communications in Mass Spectrometry, 20 (7), 1053-1060. (doi:10.1002/rcm.2408).

Record type: Article

Abstract

Pencil lead is shown to be an effective matrix and calibrant in matrix-assisted laser desorption/ ionisation (MALDI) mass spectrometry. Various groups of analytes, including peptides, polymers and actinide metals, can be readily ionised using MALDI when deposited onto a pencil lead matrix. The matrix is seen to have advantages in sample preparation relating to its hydrophobic properties and almost complete suppression of the matrix during analysis. Using pencil lead as a matrix is a quick and convenient method of qualitative analysis and has been shown to be quantitative for the isotope ratio analysis of actinide metals

Full text not available from this repository.

More information

Published date: April 2006

Identifiers

Local EPrints ID: 147777
URI: http://eprints.soton.ac.uk/id/eprint/147777
ISSN: 0951-4198
PURE UUID: 32763713-ed34-4916-8766-83e123387eee
ORCID for John Langley: ORCID iD orcid.org/0000-0002-8323-7235
ORCID for Julie Herniman: ORCID iD orcid.org/0000-0003-4834-1093

Catalogue record

Date deposited: 21 Jun 2010 13:15
Last modified: 03 Dec 2019 02:04

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×