Enantioselective synthesis of tetrafluorinated glucose and galactose
Enantioselective synthesis of tetrafluorinated glucose and galactose
Polyfluorinated carbohydrates have emerged as interesting probes to investigate “polar hydrophobicity” effect(s) in protein?carbohydrate interactions. A convenient enantioselective synthesis of tetrafluorinated analogues of two of the most important monosaccharides, d-glucose and d-galactose, is reported, as well as our first results regarding the glycosylation of these sugar analogues.
3673-3676
Timofte, Roxana S.
3f3248ca-0730-48fe-b2b4-b6fa52b499f2
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba
4 September 2008
Timofte, Roxana S.
3f3248ca-0730-48fe-b2b4-b6fa52b499f2
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba
Timofte, Roxana S. and Linclau, Bruno
(2008)
Enantioselective synthesis of tetrafluorinated glucose and galactose.
Organic Letters, 10 (17), .
(doi:10.1021/ol801272e).
Abstract
Polyfluorinated carbohydrates have emerged as interesting probes to investigate “polar hydrophobicity” effect(s) in protein?carbohydrate interactions. A convenient enantioselective synthesis of tetrafluorinated analogues of two of the most important monosaccharides, d-glucose and d-galactose, is reported, as well as our first results regarding the glycosylation of these sugar analogues.
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Published date: 4 September 2008
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Local EPrints ID: 147927
URI: http://eprints.soton.ac.uk/id/eprint/147927
ISSN: 1523-7060
PURE UUID: 3f4817e7-7e0f-4071-9d3a-0202e793aad9
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Date deposited: 27 Apr 2010 08:25
Last modified: 14 Mar 2024 02:44
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Author:
Roxana S. Timofte
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