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Enantioselective synthesis of tetrafluorinated glucose and galactose

Enantioselective synthesis of tetrafluorinated glucose and galactose
Enantioselective synthesis of tetrafluorinated glucose and galactose
Polyfluorinated carbohydrates have emerged as interesting probes to investigate “polar hydrophobicity” effect(s) in protein?carbohydrate interactions. A convenient enantioselective synthesis of tetrafluorinated analogues of two of the most important monosaccharides, d-glucose and d-galactose, is reported, as well as our first results regarding the glycosylation of these sugar analogues.
1523-7060
3673-3676
Timofte, Roxana S.
3f3248ca-0730-48fe-b2b4-b6fa52b499f2
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba
Timofte, Roxana S.
3f3248ca-0730-48fe-b2b4-b6fa52b499f2
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba

Timofte, Roxana S. and Linclau, Bruno (2008) Enantioselective synthesis of tetrafluorinated glucose and galactose. Organic Letters, 10 (17), 3673-3676. (doi:10.1021/ol801272e).

Record type: Article

Abstract

Polyfluorinated carbohydrates have emerged as interesting probes to investigate “polar hydrophobicity” effect(s) in protein?carbohydrate interactions. A convenient enantioselective synthesis of tetrafluorinated analogues of two of the most important monosaccharides, d-glucose and d-galactose, is reported, as well as our first results regarding the glycosylation of these sugar analogues.

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Published date: 4 September 2008

Identifiers

Local EPrints ID: 147927
URI: http://eprints.soton.ac.uk/id/eprint/147927
ISSN: 1523-7060
PURE UUID: 3f4817e7-7e0f-4071-9d3a-0202e793aad9
ORCID for Bruno Linclau: ORCID iD orcid.org/0000-0001-8762-0170

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Date deposited: 27 Apr 2010 08:25
Last modified: 12 Nov 2019 01:53

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