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Fatty acids and immune function: relevance to inflammatory bowel diseases

Fatty acids and immune function: relevance to inflammatory bowel diseases
Fatty acids and immune function: relevance to inflammatory bowel diseases
Fatty acids may influence immune function through a variety of mechanisms; many
of these are associated with changes in fatty acid composition of immune cell membranes.
Eicosanoids produced from arachidonic acid have roles in inflammation
and immunity. Increased membrane content of n-3 fatty acids results in a changed
pattern of production of eicosanoids, resolvins, and cytokines. Changing the fatty
acid composition of immune cells also affects T cell reactivity and antigen presentation.
Little attention has been paid to the influence of fatty acids on the gutassociated
lymphoid tissue. However, there has been considerable interest in fatty acids and gut inflammation
arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid, fish oil, inflammation, eicosanoid, cytokine, macrophage, lymphocyte
0883-0185
506-534
Calder, Phillip C.
1797e54f-378e-4dcb-80a4-3e30018f07a6
Calder, Phillip C.
1797e54f-378e-4dcb-80a4-3e30018f07a6

Calder, Phillip C. (2009) Fatty acids and immune function: relevance to inflammatory bowel diseases. International Reviews of Immunology, 28 (6), 506-534. (doi:10.3109/08830180903197480).

Record type: Article

Abstract

Fatty acids may influence immune function through a variety of mechanisms; many
of these are associated with changes in fatty acid composition of immune cell membranes.
Eicosanoids produced from arachidonic acid have roles in inflammation
and immunity. Increased membrane content of n-3 fatty acids results in a changed
pattern of production of eicosanoids, resolvins, and cytokines. Changing the fatty
acid composition of immune cells also affects T cell reactivity and antigen presentation.
Little attention has been paid to the influence of fatty acids on the gutassociated
lymphoid tissue. However, there has been considerable interest in fatty acids and gut inflammation

Full text not available from this repository.

More information

Published date: December 2009
Keywords: arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid, fish oil, inflammation, eicosanoid, cytokine, macrophage, lymphocyte

Identifiers

Local EPrints ID: 148157
URI: https://eprints.soton.ac.uk/id/eprint/148157
ISSN: 0883-0185
PURE UUID: 5b5a5dcb-5d30-474c-b1b6-7cbccbec09e4

Catalogue record

Date deposited: 27 Apr 2010 14:00
Last modified: 17 Jul 2019 00:03

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