Fatty acids and immune function: relevance to inflammatory bowel diseases
Fatty acids and immune function: relevance to inflammatory bowel diseases
Fatty acids may influence immune function through a variety of mechanisms; many
of these are associated with changes in fatty acid composition of immune cell membranes.
Eicosanoids produced from arachidonic acid have roles in inflammation
and immunity. Increased membrane content of n-3 fatty acids results in a changed
pattern of production of eicosanoids, resolvins, and cytokines. Changing the fatty
acid composition of immune cells also affects T cell reactivity and antigen presentation.
Little attention has been paid to the influence of fatty acids on the gutassociated
lymphoid tissue. However, there has been considerable interest in fatty acids and gut inflammation
arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid, fish oil, inflammation, eicosanoid, cytokine, macrophage, lymphocyte
506-534
Calder, Phillip C.
1797e54f-378e-4dcb-80a4-3e30018f07a6
December 2009
Calder, Phillip C.
1797e54f-378e-4dcb-80a4-3e30018f07a6
Calder, Phillip C.
(2009)
Fatty acids and immune function: relevance to inflammatory bowel diseases.
International Reviews of Immunology, 28 (6), .
(doi:10.3109/08830180903197480).
Abstract
Fatty acids may influence immune function through a variety of mechanisms; many
of these are associated with changes in fatty acid composition of immune cell membranes.
Eicosanoids produced from arachidonic acid have roles in inflammation
and immunity. Increased membrane content of n-3 fatty acids results in a changed
pattern of production of eicosanoids, resolvins, and cytokines. Changing the fatty
acid composition of immune cells also affects T cell reactivity and antigen presentation.
Little attention has been paid to the influence of fatty acids on the gutassociated
lymphoid tissue. However, there has been considerable interest in fatty acids and gut inflammation
This record has no associated files available for download.
More information
Published date: December 2009
Keywords:
arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid, fish oil, inflammation, eicosanoid, cytokine, macrophage, lymphocyte
Identifiers
Local EPrints ID: 148157
URI: http://eprints.soton.ac.uk/id/eprint/148157
ISSN: 0883-0185
PURE UUID: 5b5a5dcb-5d30-474c-b1b6-7cbccbec09e4
Catalogue record
Date deposited: 27 Apr 2010 14:00
Last modified: 14 Mar 2024 02:39
Export record
Altmetrics
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
