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Responsiveness of self-reported and therapist-rated upper extremity structural impairment and functional outcome measures in early rheumatoid arthritis

Responsiveness of self-reported and therapist-rated upper extremity structural impairment and functional outcome measures in early rheumatoid arthritis
Responsiveness of self-reported and therapist-rated upper extremity structural impairment and functional outcome measures in early rheumatoid arthritis
Objective: to provide a responsiveness analysis of the self-report and therapist-rated upper extremity functional outcome measures used in a rehabilitation trial.

Methods: a variety of commonly used therapist-assessed and self-report structural impairment and functional outcome measures were compared for the ability to detect and measure change in wrist and hand status in an early rheumatoid arthritis population over 12 months. Responsiveness was measured using the standardized response mean (SRM) and effect size (ES).

Results: the most responsive measures were the Michigan Hand Outcomes Questionnaire (SRM 0.49 [95% confidence interval (95% CI) 0.27, 0.72], ES = 0.37 [95% CI 0.21, 0.54]), dominant metacarpophalangeal joint ulnar deviation (SRM 0.46 [95% CI 0.27, 0.65], ES = 0.58 [95% CI 0.34, 0.82]), and mean power handgrip test (SRM 0.45 [95% CI 0.26, 0.64], ES = 0.32 [95% CI 0.18, 0.45]) The least responsive measure was the Health Assessment Questionnaire (SRM -0.12 [95% CI -0.31, 0.08], ES = -0.08 [95% CI -0.21, 0.05]).

Conclusion: over 12 months, there was substantial variation in wrist and hand outcome measures to detect change over time in an early RA population. Careful consideration is required to choose the most appropriate measure that can detect change.
0893-7524
274-278
Adams, Jo
6e38b8bb-9467-4585-86e4-14062b02bcba
Mullee, Mark
fd3f91c3-5e95-4f56-8d73-260824eeb362
Burridge, Jane
0110e9ea-0884-4982-a003-cb6307f38f64
Hammond, Alison
bcbbb91c-3084-4c68-8aa6-4a5062703ecb
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Adams, Jo
6e38b8bb-9467-4585-86e4-14062b02bcba
Mullee, Mark
fd3f91c3-5e95-4f56-8d73-260824eeb362
Burridge, Jane
0110e9ea-0884-4982-a003-cb6307f38f64
Hammond, Alison
bcbbb91c-3084-4c68-8aa6-4a5062703ecb
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6

Adams, Jo, Mullee, Mark, Burridge, Jane, Hammond, Alison and Cooper, Cyrus (2010) Responsiveness of self-reported and therapist-rated upper extremity structural impairment and functional outcome measures in early rheumatoid arthritis. Arthritis Care and Research, 62 (2), 274-278. (doi:10.1002/acr.20078).

Record type: Article

Abstract

Objective: to provide a responsiveness analysis of the self-report and therapist-rated upper extremity functional outcome measures used in a rehabilitation trial.

Methods: a variety of commonly used therapist-assessed and self-report structural impairment and functional outcome measures were compared for the ability to detect and measure change in wrist and hand status in an early rheumatoid arthritis population over 12 months. Responsiveness was measured using the standardized response mean (SRM) and effect size (ES).

Results: the most responsive measures were the Michigan Hand Outcomes Questionnaire (SRM 0.49 [95% confidence interval (95% CI) 0.27, 0.72], ES = 0.37 [95% CI 0.21, 0.54]), dominant metacarpophalangeal joint ulnar deviation (SRM 0.46 [95% CI 0.27, 0.65], ES = 0.58 [95% CI 0.34, 0.82]), and mean power handgrip test (SRM 0.45 [95% CI 0.26, 0.64], ES = 0.32 [95% CI 0.18, 0.45]) The least responsive measure was the Health Assessment Questionnaire (SRM -0.12 [95% CI -0.31, 0.08], ES = -0.08 [95% CI -0.21, 0.05]).

Conclusion: over 12 months, there was substantial variation in wrist and hand outcome measures to detect change over time in an early RA population. Careful consideration is required to choose the most appropriate measure that can detect change.

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More information

Published date: February 2010
Organisations: Medicine

Identifiers

Local EPrints ID: 150253
URI: https://eprints.soton.ac.uk/id/eprint/150253
ISSN: 0893-7524
PURE UUID: 59a54f52-ff0f-4e6e-ba82-949285466e66
ORCID for Jo Adams: ORCID iD orcid.org/0000-0003-1765-7060
ORCID for Jane Burridge: ORCID iD orcid.org/0000-0003-3497-6725
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709

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Date deposited: 04 May 2010 15:44
Last modified: 20 Jul 2019 01:18

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