Ultrasound measurements of visceral and subcutaneous abdominal thickness to predict abdominal adiposity among older men and women.
Ultrasound measurements of visceral and subcutaneous abdominal thickness to predict abdominal adiposity among older men and women.
Accurate measures of visceral and abdominal subcutaneous fat are essential for investigating the pathophysiology of obesity. Classical anthropometric measures such as waist and hip circumference cannot distinguish between these two fat depots. Direct imaging methods such as computed tomography and magnetic resonance imaging (MRI) are restricted in large-scale studies due to practical and ethical issues. We aimed to establish whether ultrasound is a valid alternative method to MRI for the quantitative assessment of abdominal fat depots in older individuals.
The study population comprised 74 white individuals (41 men and 33 women, aged 67–76 years) participating in the Hertfordshire Birth Cohort Physical Activity trial. Anthropometry included height, weight, waist and hip circumferences. Abdominal fat was measured by ultrasound in two compartments: visceral fat defined as the depth from the peritoneum to the lumbar spine; and subcutaneous fat defined as the depth from the skin to the abdominal muscles and compared to reference measures by MRI (10-mm single-slice image).
Ultrasound measures were positively correlated with MRI measures of visceral and subcutaneous fat (visceral: r = 0.82 and r = 0.80 in men and women, respectively; subcutaneous: r = 0.63 and 0.68 in men and women, respectively). In multiple regression models, the addition of ultrasound measures significantly improved the prediction of visceral fat and subcutaneous fat in both men and women over and above the contribution of standard anthropometric variables. In conclusion, ultrasound is a valid method to estimate visceral fat in epidemiological studies of older men and women when MRI and computed tomography are not feasible.
625-631
De Lucia Rolfe, Ema
79cd36f9-4055-43d9-9f98-c5903ec23a59
Sleigh, Alison
b948a8de-00fb-436f-ace2-aa2310964c71
Finucane, Francis M.
18a42c88-6fec-44b6-a10e-c8fdb32e62a9
Brage, Soren
3705fa6b-2018-4ad6-9143-fa9240ec0fc9
Stolk, Ronald P.
f3e373c4-d7a3-4e2e-aefa-65d85f29962c
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Sharp, Stephen J.
65e1326f-97f8-4654-b75c-15d046f00532
Wareham, Nicholas J.
bbc18cd9-3512-4ca6-806c-75c9a01e5adf
Ong, Ken K.
11be427c-95c2-4c09-9000-2a915a247885
2010
De Lucia Rolfe, Ema
79cd36f9-4055-43d9-9f98-c5903ec23a59
Sleigh, Alison
b948a8de-00fb-436f-ace2-aa2310964c71
Finucane, Francis M.
18a42c88-6fec-44b6-a10e-c8fdb32e62a9
Brage, Soren
3705fa6b-2018-4ad6-9143-fa9240ec0fc9
Stolk, Ronald P.
f3e373c4-d7a3-4e2e-aefa-65d85f29962c
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Sharp, Stephen J.
65e1326f-97f8-4654-b75c-15d046f00532
Wareham, Nicholas J.
bbc18cd9-3512-4ca6-806c-75c9a01e5adf
Ong, Ken K.
11be427c-95c2-4c09-9000-2a915a247885
De Lucia Rolfe, Ema, Sleigh, Alison, Finucane, Francis M., Brage, Soren, Stolk, Ronald P., Cooper, Cyrus, Sharp, Stephen J., Wareham, Nicholas J. and Ong, Ken K.
(2010)
Ultrasound measurements of visceral and subcutaneous abdominal thickness to predict abdominal adiposity among older men and women.
Obesity, 18 (3), .
(doi:10.1038/oby.2009.309).
Abstract
Accurate measures of visceral and abdominal subcutaneous fat are essential for investigating the pathophysiology of obesity. Classical anthropometric measures such as waist and hip circumference cannot distinguish between these two fat depots. Direct imaging methods such as computed tomography and magnetic resonance imaging (MRI) are restricted in large-scale studies due to practical and ethical issues. We aimed to establish whether ultrasound is a valid alternative method to MRI for the quantitative assessment of abdominal fat depots in older individuals.
The study population comprised 74 white individuals (41 men and 33 women, aged 67–76 years) participating in the Hertfordshire Birth Cohort Physical Activity trial. Anthropometry included height, weight, waist and hip circumferences. Abdominal fat was measured by ultrasound in two compartments: visceral fat defined as the depth from the peritoneum to the lumbar spine; and subcutaneous fat defined as the depth from the skin to the abdominal muscles and compared to reference measures by MRI (10-mm single-slice image).
Ultrasound measures were positively correlated with MRI measures of visceral and subcutaneous fat (visceral: r = 0.82 and r = 0.80 in men and women, respectively; subcutaneous: r = 0.63 and 0.68 in men and women, respectively). In multiple regression models, the addition of ultrasound measures significantly improved the prediction of visceral fat and subcutaneous fat in both men and women over and above the contribution of standard anthropometric variables. In conclusion, ultrasound is a valid method to estimate visceral fat in epidemiological studies of older men and women when MRI and computed tomography are not feasible.
This record has no associated files available for download.
More information
Published date: 2010
Identifiers
Local EPrints ID: 150719
URI: http://eprints.soton.ac.uk/id/eprint/150719
ISSN: 1930-7381
PURE UUID: 39743df1-480e-47cb-bd5d-1b666139d9fa
Catalogue record
Date deposited: 06 May 2010 09:28
Last modified: 18 Mar 2024 02:44
Export record
Altmetrics
Contributors
Author:
Ema De Lucia Rolfe
Author:
Alison Sleigh
Author:
Francis M. Finucane
Author:
Soren Brage
Author:
Ronald P. Stolk
Author:
Stephen J. Sharp
Author:
Nicholas J. Wareham
Author:
Ken K. Ong
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics