The University of Southampton
University of Southampton Institutional Repository

Clinical, emotional and social factors associated with quality of life in chronic pancreatitis.

Record type: Article

Background:

In chronic pancreatitis (CP), a debilitating, progressive and incurable disease, patients' wellbeing is considerably impaired, but the different factors affecting quality of life (QoL), have not been identified yet.

Methods:

69 patients with CP were evaluated (M/F 55/14; mean age 46.6 +/- 10.05 years). Different degrees of pancreatic damage were defined using the Cambridge classification; pain intensity and frequency were assessed using pain index. QoL was measured using EORTC QLQ-C30 and the PAN26 questionnaire. Although developed for pancreatic cancer, the C30/PAN26 has been validated for chronic pancreatitis.

Results:

Digestive symptoms, financial difficulties, fear of future health and general pain scales showed considerable effects of CP on QoL. We observed significant negative correlation between mean QoL scores and pain index in almost all domains (p < 0.001, p < 0.05). Pain intensity affects QoL scales more often than pain frequency. BMI correlated positively with QoL in global health status, altered bowel habits, body image and satisfaction with health care domains (p < 0.01, p < 0.05).

Conclusion:

Pain index, BMI, Cambridge classification and disease duration are the most important factors adversely affecting QoL in CP. Measurement of QoL is essential in the disease management and improves the knowledge of psychosocial functioning of these patients. and IAP.

Full text not available from this repository.

Citation

Mokrowiecka, A., Pinkowski, D., Malecka-Panas, E. and Johnson, C. D. (2010) Clinical, emotional and social factors associated with quality of life in chronic pancreatitis. Pancreatology, 10, (1), pp. 39-46. (doi:10.1159/000225920).

More information

Published date: 2010
Keywords: chronic pancreatitis, EORTC QLQ-C30, EORTC PAN26, quality of life

Identifiers

Local EPrints ID: 150879
URI: http://eprints.soton.ac.uk/id/eprint/150879
ISSN: 1424-3903
PURE UUID: ef29915f-90a5-490a-b851-a7be7f19438b

Catalogue record

Date deposited: 07 May 2010 08:11
Last modified: 18 Jul 2017 12:56

Export record

Altmetrics

Contributors

Author: A. Mokrowiecka
Author: D. Pinkowski
Author: E. Malecka-Panas
Author: C. D. Johnson

University divisions


Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×