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Developmental dysplasia of the hip and occult neurology

Developmental dysplasia of the hip and occult neurology
Developmental dysplasia of the hip and occult neurology
Developmental dysplasia of the hip (DDH) is a neonatal condition with various causes. Neuromuscular dysplasia of the hip (NDH) is a sequel of neuromuscular disease, and generally presents later in childhood than DDH. Some evidence, however, supports a concept of a neuromuscular etiology of DDH: (1) a high prevalence of spinal dysraphism in DDH; and (2) abnormal sensory evoked potentials in 31% of DDH patients.

To explore this suggestion we ascertained the presence of neuromuscular disease within a cohort of DDH patients, and asked whether the neuromuscular condition is the initial etiology of the dysplasia or a coincidental finding. We retrospectively reviewed patients presenting with DDH. Only those with an initial diagnosis of DDH and a subsequent diagnosis of a neuromuscular condition were assessed. Fifteen of 560 patients fulfilled the criteria, however the presence of true DDH within this group was minimal, as several cases emerged as early presenting NDH.

We therefore believe it unlikely DDH has a substantial neurological etiology.

Level of evidence:

Level III, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.
0009-921X
871-877
Luther, Alison Z.
3bfe61e6-1aeb-4471-83a8-881eb68f8ec0
Clarke, Nicholas M.
93fced14-03bd-4af8-8ec7-086b1a306985
Luther, Alison Z.
3bfe61e6-1aeb-4471-83a8-881eb68f8ec0
Clarke, Nicholas M.
93fced14-03bd-4af8-8ec7-086b1a306985

Luther, Alison Z. and Clarke, Nicholas M. (2008) Developmental dysplasia of the hip and occult neurology. Clinical Orthopaedics and Related Research, 466 (4), 871-877. (doi:10.1007/s11999-008-0118-6.).

Record type: Article

Abstract

Developmental dysplasia of the hip (DDH) is a neonatal condition with various causes. Neuromuscular dysplasia of the hip (NDH) is a sequel of neuromuscular disease, and generally presents later in childhood than DDH. Some evidence, however, supports a concept of a neuromuscular etiology of DDH: (1) a high prevalence of spinal dysraphism in DDH; and (2) abnormal sensory evoked potentials in 31% of DDH patients.

To explore this suggestion we ascertained the presence of neuromuscular disease within a cohort of DDH patients, and asked whether the neuromuscular condition is the initial etiology of the dysplasia or a coincidental finding. We retrospectively reviewed patients presenting with DDH. Only those with an initial diagnosis of DDH and a subsequent diagnosis of a neuromuscular condition were assessed. Fifteen of 560 patients fulfilled the criteria, however the presence of true DDH within this group was minimal, as several cases emerged as early presenting NDH.

We therefore believe it unlikely DDH has a substantial neurological etiology.

Level of evidence:

Level III, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.

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Published date: April 2008

Identifiers

Local EPrints ID: 151281
URI: http://eprints.soton.ac.uk/id/eprint/151281
ISSN: 0009-921X
PURE UUID: 65407135-b294-4a2d-a7a0-5f151269142e

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Date deposited: 10 May 2010 10:43
Last modified: 14 Mar 2024 01:19

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Contributors

Author: Alison Z. Luther
Author: Nicholas M. Clarke

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