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Prognostic factors that determine visual outcome following cataract surgery complicated by vitreous loss

Konstantopoulos, Aristides, Yadegarfar, Ghasem, Madhusudhana, Khrishnapa, Canning, Chris, Luff, Andrew, Anderson, David and Hossain, Parwez (2009) Prognostic factors that determine visual outcome following cataract surgery complicated by vitreous loss European Journal of Ophthalmology, 19, (2), pp. 247-253. (doi:10.1007/s10792-008-9214-6). (PMID:19253242).

Record type: Article


Purpose: To identify prognostic factors that determine visual outcome following phacoemulsification cataract surgery complicated by vitreous loss.

Methods: A retrospective cohort study. All cases of vitreous loss during phacoemulsification surgery at a university hospital, between June 2000 and December 2005, were identified from the hospital computer database. By reviewing the medical notes, preoperative, intraoperative, and postoperative data were collected. Outcome of interest was presence of poor visual outcome (best-corrected visual acuity [BCVA] <6/12). Chi-square and Mann-Whitney U tests were used to compare groups of poor and good visual outcome.

Results: A total of 230 consecutive cases (eyes) were identified; medical notes were available for 228. Mean patient age was 78.4 years (SD 11); median follow-up 13.4 weeks (range 1-203). In multivariable logistic regression analysis poor visual outcome was independently associated with poor preoperative vision (BCVA <6/12) (OR 3.78, 95% CI 1.76-8.11), age-related macular degeneration (OR 3.04, 95% CI 1.16-8.00), cystoid macular edema (OR 3.85, 95% CI 1.29-11.51), and secondary pars plana vitrectomy (PPV) for nuclear fragment loss (OR 4.42, 95% CI 1.03-19.02). Primary PPV for nuclear fragment loss, age >70, ocular comorbidity, axial length, vitreous loss during irrigation/aspiration, or lens implantation, anterior chamber lens, and secondary lens implantation were not significant associations (p>or= 0.05). In 33 (14.5%) eyes BCVA was reduced by at least one Snellen line compared to before surgery.

Conclusions: Poor visual outcome was associated with poor preoperative vision, age-related macular degeneration, cystoid macular edema, and secondary PPV following nuclear fragment loss. Primary PPV for nuclear fragment loss was not a significant association.

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Published date: 19 April 2009
Keywords: cataract surgery, visual outcome, vitreous loss


Local EPrints ID: 154137
PURE UUID: 0888d0e3-980c-4d82-a08d-6c0a5f67f677

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Date deposited: 24 May 2010 14:49
Last modified: 18 Jul 2017 12:47

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Author: Aristides Konstantopoulos
Author: Ghasem Yadegarfar
Author: Khrishnapa Madhusudhana
Author: Chris Canning
Author: Andrew Luff
Author: David Anderson
Author: Parwez Hossain

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