The University of Southampton
University of Southampton Institutional Repository

Coding characteristics of spiking local interneurons during imposed limb movements in the locust

Record type: Article

The performance of adaptive behavior relies on continuous sensory feedback to produce relevant modifications to central motor patterns. The femoral chordotonal organ (FeCO) of the legs of the desert locust monitors the movements of the tibia about the femoro-tibial joint. A ventral midline population of spiking local interneurons in the metathoracic ganglia integrates inputs from the FeCO. We used a Wiener kernel cross-correlation method combined with a Gaussian white noise stimulation of the FeCO to completely characterize and model the output dynamics of the ventral midline population of interneurons. A wide range of responses were observed, and interneurons could be classified into three broad groups that received excitatory and inhibitory or principally inhibitory or excitatory synaptic inputs from the FeCO. Interneurons that received mixed inputs also had the greatest linear responses but primarily responded to extension of the tibia and were mostly sensitive to stimulus velocity. Interneurons that received principally inhibitory inputs were sensitive to extension and to joint position. A small group of interneurons received purely excitatory synaptic inputs and were also sensitive to tibial extension. In addition to capturing the linear and nonlinear dynamics of this population of interneurons, first- and second-order Wiener kernels revealed that the dynamics of the interneurons in the population were graded and formed a spectrum of responses whereby the activity of many cells appeared to be required to adequately describe a particular stimulus characteristic, typical of population coding.

PDF Vidal-Gadea_et_al__submitted_.pdf - Other
Restricted to Repository staff only
Download (240kB)

Citation

Vidal-Gadea, A.G., Jing, X.J., Simpson, D.M., Dewhirst, O.P., Kondoh, Y., Allen, R. and Newland, P.L. (2010) Coding characteristics of spiking local interneurons during imposed limb movements in the locust Journal of Neurophysiology, 103, (2), pp. 603-615. (doi:10.1152/jn.00510.2009). (PMID:19955290).

More information

Published date: February 2010
Organisations: Biological Sciences

Identifiers

Local EPrints ID: 154977
URI: http://eprints.soton.ac.uk/id/eprint/154977
ISSN: 0022-3077
PURE UUID: 0b471161-efe1-4bd5-af21-a02448b879e7

Catalogue record

Date deposited: 26 May 2010 14:11
Last modified: 18 Jul 2017 12:46

Export record

Altmetrics

Contributors

Author: A.G. Vidal-Gadea
Author: X.J. Jing
Author: D.M. Simpson
Author: O.P. Dewhirst
Author: Y. Kondoh
Author: R. Allen
Author: P.L. Newland

University divisions


Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×