Mathematical modelling of magnetically targeted drug delivery
Mathematical modelling of magnetically targeted drug delivery
A mathematical model for targeted drug delivery using magnetic particles is developed. This includes a diffusive flux of particles arising from interactions between erythrocytes in the microcirculation. The model is used to track particles in a vessel network. Magnetic field design is discussed and we show that it is impossible to specifically target internal regions using an externally applied field
magnetic targeting, drug delivery, shear-induced diffusion, network model, magnetic field design, simulation
455-463
Grief, Andrew D.
74102369-1788-4828-ab01-f3b4834d2ee0
Richardson, Giles
3fd8e08f-e615-42bb-a1ff-3346c5847b91
May 2005
Grief, Andrew D.
74102369-1788-4828-ab01-f3b4834d2ee0
Richardson, Giles
3fd8e08f-e615-42bb-a1ff-3346c5847b91
Grief, Andrew D. and Richardson, Giles
(2005)
Mathematical modelling of magnetically targeted drug delivery.
Journal of Magnetism and Magnetic Materials, 293 (1), .
(doi:10.1016/j.jmmm.2005.02.040).
Abstract
A mathematical model for targeted drug delivery using magnetic particles is developed. This includes a diffusive flux of particles arising from interactions between erythrocytes in the microcirculation. The model is used to track particles in a vessel network. Magnetic field design is discussed and we show that it is impossible to specifically target internal regions using an externally applied field
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Journal_of_Magnetism_and_Magnetic_Materials_2005_Grief.pdf
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Published date: May 2005
Additional Information:
Proceedings of the Fifth International Conference on Scientific and Clinical Apllications of Magnetic Carriers, Lyon, France, 20-22 May 2004
Keywords:
magnetic targeting, drug delivery, shear-induced diffusion, network model, magnetic field design, simulation
Identifiers
Local EPrints ID: 156357
URI: http://eprints.soton.ac.uk/id/eprint/156357
ISSN: 0304-8853
PURE UUID: 826eed2a-dbf1-47df-8eb5-f47e26e9c506
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Date deposited: 02 Jul 2010 08:30
Last modified: 14 Mar 2024 02:54
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Author:
Andrew D. Grief
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