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Mathematical modelling of magnetically targeted drug delivery

Mathematical modelling of magnetically targeted drug delivery
Mathematical modelling of magnetically targeted drug delivery
A mathematical model for targeted drug delivery using magnetic particles is developed. This includes a diffusive flux of particles arising from interactions between erythrocytes in the microcirculation. The model is used to track particles in a vessel network. Magnetic field design is discussed and we show that it is impossible to specifically target internal regions using an externally applied field
magnetic targeting, drug delivery, shear-induced diffusion, network model, magnetic field design, simulation
0304-8853
455-463
Grief, Andrew D.
74102369-1788-4828-ab01-f3b4834d2ee0
Richardson, Giles
3fd8e08f-e615-42bb-a1ff-3346c5847b91
Grief, Andrew D.
74102369-1788-4828-ab01-f3b4834d2ee0
Richardson, Giles
3fd8e08f-e615-42bb-a1ff-3346c5847b91

Grief, Andrew D. and Richardson, Giles (2005) Mathematical modelling of magnetically targeted drug delivery. Journal of Magnetism and Magnetic Materials, 293 (1), 455-463. (doi:10.1016/j.jmmm.2005.02.040).

Record type: Article

Abstract

A mathematical model for targeted drug delivery using magnetic particles is developed. This includes a diffusive flux of particles arising from interactions between erythrocytes in the microcirculation. The model is used to track particles in a vessel network. Magnetic field design is discussed and we show that it is impossible to specifically target internal regions using an externally applied field

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More information

Published date: May 2005
Additional Information: Proceedings of the Fifth International Conference on Scientific and Clinical Apllications of Magnetic Carriers, Lyon, France, 20-22 May 2004
Keywords: magnetic targeting, drug delivery, shear-induced diffusion, network model, magnetic field design, simulation

Identifiers

Local EPrints ID: 156357
URI: http://eprints.soton.ac.uk/id/eprint/156357
ISSN: 0304-8853
PURE UUID: 826eed2a-dbf1-47df-8eb5-f47e26e9c506

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Date deposited: 02 Jul 2010 08:30
Last modified: 26 Apr 2022 22:11

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Contributors

Author: Andrew D. Grief

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