Modelling production of extracellular polymeric substances in a Pseudomonas aeruginosa chemostat culture
Modelling production of extracellular polymeric substances in a Pseudomonas aeruginosa chemostat culture
Formation of extracellular polymeric substances (EPSs) by mucoid Pseudomonas aeruginosa was investigated using literature data from chemostat cultures. The data were used to calibrate a product formation regime allowing substrate sufficient and endogenous EPS formation. Yield coefficients for both formation conditions were elucidated based on metabolic pathway analysis. Growth and non-growth related specific formation rates of 0.18 g CEPS/g Ccell/h and 0.03 1/h were estimated, respectively. The exogenous and endogenous EPS yield was found to be 0.77 g CEPS/g Cglu and 0.79 g CEPS/g Ccell, respectively. Being structurally equivalent to comprehensive maintenance models, this model allows for non-growth related product formation, showing the same quality of fit as previous models restricted to exogenous EPS precursors.
129-134
Kommedal, R.
e6e3158c-a464-461c-a1e3-c3a5d0018964
Bakke, R.
8056a992-2dfc-4f10-baf0-b0dd62140a67
Dockery, J.
aa589979-f803-4081-ae63-f4cd1ed21175
Stoodley, P.
08614665-92a9-4466-806e-20c6daeb483f
2001
Kommedal, R.
e6e3158c-a464-461c-a1e3-c3a5d0018964
Bakke, R.
8056a992-2dfc-4f10-baf0-b0dd62140a67
Dockery, J.
aa589979-f803-4081-ae63-f4cd1ed21175
Stoodley, P.
08614665-92a9-4466-806e-20c6daeb483f
Kommedal, R., Bakke, R., Dockery, J. and Stoodley, P.
(2001)
Modelling production of extracellular polymeric substances in a Pseudomonas aeruginosa chemostat culture.
Water Science & Technology, 43 (6), .
Abstract
Formation of extracellular polymeric substances (EPSs) by mucoid Pseudomonas aeruginosa was investigated using literature data from chemostat cultures. The data were used to calibrate a product formation regime allowing substrate sufficient and endogenous EPS formation. Yield coefficients for both formation conditions were elucidated based on metabolic pathway analysis. Growth and non-growth related specific formation rates of 0.18 g CEPS/g Ccell/h and 0.03 1/h were estimated, respectively. The exogenous and endogenous EPS yield was found to be 0.77 g CEPS/g Cglu and 0.79 g CEPS/g Ccell, respectively. Being structurally equivalent to comprehensive maintenance models, this model allows for non-growth related product formation, showing the same quality of fit as previous models restricted to exogenous EPS precursors.
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Published date: 2001
Organisations:
Engineering Mats & Surface Engineerg Gp
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Local EPrints ID: 157455
URI: http://eprints.soton.ac.uk/id/eprint/157455
ISSN: 0273-1223
PURE UUID: ad3c43d4-cf22-4025-9cf0-cef004d45feb
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Date deposited: 09 Jun 2010 16:35
Last modified: 09 Jan 2022 03:32
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Author:
R. Kommedal
Author:
R. Bakke
Author:
J. Dockery
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