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Tropical infectious diseases: Urbanization, malaria transmission and disease burden in Africa

Tropical infectious diseases: Urbanization, malaria transmission and disease burden in Africa
Tropical infectious diseases: Urbanization, malaria transmission and disease burden in Africa
Many attempts have been made to quantify Africa’s malaria burden but none has addressed how urbanization will affect disease transmission and outcome, and therefore mortality and morbidity estimates. In 2003, 39% of Africa’s 850 million people lived in urban settings; by 2030, 54% of Africans are expected to do so. We present the results of a series of entomological, parasitological and behavioural metaanalyses of studies that have investigated the effect of urbanization on malaria in Africa. We describe the effect of urbanization on both the impact of malaria transmission and the concomitant improvements in access to preventative and curative measures. Using these data, we have recalculated estimates of populations at risk of malaria and the resulting mortality. We find there were 1,068,505 malaria deaths in Africa in 2000 — a modest 6.7% reduction over previous iterations. The public-health implications of these findings and revised estimates are discussed.
malaria, Plasmodium falciparum, entomological inoculation rate (EIR), biting rate, sporozoite index, transmission, disease control, africa
1740-1526
81-90
Hay, S.I.
ad00c295-7b71-4d56-83d5-2c936e6b77d2
Guerra, C.
e6908e66-b301-4780-8bcc-f1f6033a616c
Tatem, A.J.
6c6de104-a5f9-46e0-bb93-a1a7c980513e
Atkinson, P.M.
96e96579-56fe-424d-a21c-17b6eed13b0b
Snow, R.W.
1df934dd-70f4-4bf1-8a98-7feb0207d796
Hay, S.I.
ad00c295-7b71-4d56-83d5-2c936e6b77d2
Guerra, C.
e6908e66-b301-4780-8bcc-f1f6033a616c
Tatem, A.J.
6c6de104-a5f9-46e0-bb93-a1a7c980513e
Atkinson, P.M.
96e96579-56fe-424d-a21c-17b6eed13b0b
Snow, R.W.
1df934dd-70f4-4bf1-8a98-7feb0207d796

Hay, S.I., Guerra, C., Tatem, A.J., Atkinson, P.M. and Snow, R.W. (2005) Tropical infectious diseases: Urbanization, malaria transmission and disease burden in Africa. Nature Reviews Microbiology, 3 (1), 81-90. (doi:10.1038/nrmicro1069). (PMID:15608702)

Record type: Article

Abstract

Many attempts have been made to quantify Africa’s malaria burden but none has addressed how urbanization will affect disease transmission and outcome, and therefore mortality and morbidity estimates. In 2003, 39% of Africa’s 850 million people lived in urban settings; by 2030, 54% of Africans are expected to do so. We present the results of a series of entomological, parasitological and behavioural metaanalyses of studies that have investigated the effect of urbanization on malaria in Africa. We describe the effect of urbanization on both the impact of malaria transmission and the concomitant improvements in access to preventative and curative measures. Using these data, we have recalculated estimates of populations at risk of malaria and the resulting mortality. We find there were 1,068,505 malaria deaths in Africa in 2000 — a modest 6.7% reduction over previous iterations. The public-health implications of these findings and revised estimates are discussed.

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Published date: January 2005
Keywords: malaria, Plasmodium falciparum, entomological inoculation rate (EIR), biting rate, sporozoite index, transmission, disease control, africa
Organisations: PHEW – P (Population Health), Remote Sensing & Spatial Analysis

Identifiers

Local EPrints ID: 15774
URI: http://eprints.soton.ac.uk/id/eprint/15774
ISSN: 1740-1526
PURE UUID: 1ab8a300-0d03-41e0-bd0c-5c2ade7b493e
ORCID for A.J. Tatem: ORCID iD orcid.org/0000-0002-7270-941X
ORCID for P.M. Atkinson: ORCID iD orcid.org/0000-0002-5489-6880

Catalogue record

Date deposited: 02 Jun 2005
Last modified: 16 Mar 2024 04:11

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Contributors

Author: S.I. Hay
Author: C. Guerra
Author: A.J. Tatem ORCID iD
Author: P.M. Atkinson ORCID iD
Author: R.W. Snow

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