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Bariatric surgery and renal function: a precarious balance between benefit and harm

Bariatric surgery and renal function: a precarious balance between benefit and harm
Bariatric surgery and renal function: a precarious balance between benefit and harm
Medical treatment of obesity and lifestyle modification have limited effectiveness in treating it in morbidly obese individuals. Importantly, bariatric surgery is regarded as the only therapy that is effective in maintaining significant weight loss in morbidly obese individuals. Despite the fact that bariatric surgery-induced weight loss is associated with a significant decrease in morbidity and mortality and improvement in renal function, bariatric surgery has recently been shown to be associated with a significant risk of nephrolithiasis. The main risk factor for nephrolithiasis is increased excretion of urinary oxalate. In this review, we discuss the association between bariatric surgery, an increased risk of renal stone formation and oxalate nephropathy.
bariatric surgery, obesity, oxalate nephropathy, renal stone
0931-0509
3142-3147
Ahmed, Mohamed H.
ed037a05-9770-4c1f-80a8-bd79fc83ee35
Byrne, Christopher D.
1370b997-cead-4229-83a7-53301ed2a43c
Ahmed, Mohamed H.
ed037a05-9770-4c1f-80a8-bd79fc83ee35
Byrne, Christopher D.
1370b997-cead-4229-83a7-53301ed2a43c

Ahmed, Mohamed H. and Byrne, Christopher D. (2010) Bariatric surgery and renal function: a precarious balance between benefit and harm. Nephrology, Dialysis, Transplantation, 25 (10), 3142-3147. (doi:10.1093/ndt/gfq347). (PMID:20566568)

Record type: Article

Abstract

Medical treatment of obesity and lifestyle modification have limited effectiveness in treating it in morbidly obese individuals. Importantly, bariatric surgery is regarded as the only therapy that is effective in maintaining significant weight loss in morbidly obese individuals. Despite the fact that bariatric surgery-induced weight loss is associated with a significant decrease in morbidity and mortality and improvement in renal function, bariatric surgery has recently been shown to be associated with a significant risk of nephrolithiasis. The main risk factor for nephrolithiasis is increased excretion of urinary oxalate. In this review, we discuss the association between bariatric surgery, an increased risk of renal stone formation and oxalate nephropathy.

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Published date: October 2010
Keywords: bariatric surgery, obesity, oxalate nephropathy, renal stone
Organisations: Medicine

Identifiers

Local EPrints ID: 158219
URI: http://eprints.soton.ac.uk/id/eprint/158219
ISSN: 0931-0509
PURE UUID: 4b81b643-9426-46ac-946c-51c2f4b469b9
ORCID for Christopher D. Byrne: ORCID iD orcid.org/0000-0001-6322-7753

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Date deposited: 16 Jun 2010 14:04
Last modified: 12 Nov 2019 01:53

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