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The role of biofilms in otolaryngologic infections: update 2007

The role of biofilms in otolaryngologic infections: update 2007
The role of biofilms in otolaryngologic infections: update 2007
Purpose of review: Biofilms have been shown to play a role in otitis media, sinusitis, cholesteatoma, tonsillitis, adenoiditis, and device infections. This article is written to review recent advances in the field. RECENT

Findings: The role of biofilms in the persistence of chronic, mucosal-based ENT-related infections was first recognized in otitis media. Definitive proof was lacking until the demonstration of bacterial biofilms on the middle-ear mucosa of children, not only with chronic otitis media with effusion, but also with recurrent otitis media. Strains of Pseudomonas aeruginosa isolated from cholesteatoma are avid biofilm formers. Biofilms have been reported in the adenoids of children with chronic rhinosinusitis, helping to explain the clinical observation that adenoidectomy can be beneficial to children with chronic otitis or chronic rhinosinusiti. Additional studies have confirmed the presence of biofilms in chronic tonsillitis. Biofilms have also been shown to be involved in infected cochlear implants and tracheotomy tubes.

Summary: The recognition that chronic otolaryngologic bacterial infections are biofilm related has been the impetus for the development of new technologies for the study of biofilms and their prevention and treatment. Understanding that chronic bacterial infections are biofilm related is fundamental to developing rationale strategies for treatment and prevention.
347-351
Post, J. Christopher
832cfa58-9254-4396-8c8f-6fb18cc6c18c
Hiller, N. Luisa
d6deb047-3a03-4a71-aaaf-34a3e2d6df41
Nistico, Laura
7a83886a-6bf1-46a1-87dd-75a120d41603
Stoodley, Paul
08614665-92a9-4466-806e-20c6daeb483f
Ehrlich, Garth D.
aa8e5162-77a6-4627-a793-acd724ed0782
Post, J. Christopher
832cfa58-9254-4396-8c8f-6fb18cc6c18c
Hiller, N. Luisa
d6deb047-3a03-4a71-aaaf-34a3e2d6df41
Nistico, Laura
7a83886a-6bf1-46a1-87dd-75a120d41603
Stoodley, Paul
08614665-92a9-4466-806e-20c6daeb483f
Ehrlich, Garth D.
aa8e5162-77a6-4627-a793-acd724ed0782

Post, J. Christopher, Hiller, N. Luisa, Nistico, Laura, Stoodley, Paul and Ehrlich, Garth D. (2007) The role of biofilms in otolaryngologic infections: update 2007. Current Opinion in Otolaryngology & Head and Neck Surgery, 15 (5), 347-351. (doi:10.1097/MOO.0b013e3282b97327).

Record type: Article

Abstract

Purpose of review: Biofilms have been shown to play a role in otitis media, sinusitis, cholesteatoma, tonsillitis, adenoiditis, and device infections. This article is written to review recent advances in the field. RECENT

Findings: The role of biofilms in the persistence of chronic, mucosal-based ENT-related infections was first recognized in otitis media. Definitive proof was lacking until the demonstration of bacterial biofilms on the middle-ear mucosa of children, not only with chronic otitis media with effusion, but also with recurrent otitis media. Strains of Pseudomonas aeruginosa isolated from cholesteatoma are avid biofilm formers. Biofilms have been reported in the adenoids of children with chronic rhinosinusitis, helping to explain the clinical observation that adenoidectomy can be beneficial to children with chronic otitis or chronic rhinosinusiti. Additional studies have confirmed the presence of biofilms in chronic tonsillitis. Biofilms have also been shown to be involved in infected cochlear implants and tracheotomy tubes.

Summary: The recognition that chronic otolaryngologic bacterial infections are biofilm related has been the impetus for the development of new technologies for the study of biofilms and their prevention and treatment. Understanding that chronic bacterial infections are biofilm related is fundamental to developing rationale strategies for treatment and prevention.

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More information

Published date: October 2007
Organisations: Engineering Mats & Surface Engineerg Gp

Identifiers

Local EPrints ID: 158295
URI: http://eprints.soton.ac.uk/id/eprint/158295
PURE UUID: 51d8bc5e-aa0a-42c5-8fcb-b0f3298f55a4
ORCID for Paul Stoodley: ORCID iD orcid.org/0000-0001-6069-273X

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Date deposited: 17 Jun 2010 13:06
Last modified: 14 Mar 2024 02:55

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Contributors

Author: J. Christopher Post
Author: N. Luisa Hiller
Author: Laura Nistico
Author: Paul Stoodley ORCID iD
Author: Garth D. Ehrlich

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