Do all systems age together?
Do all systems age together?
Background: Aging changes in different body system are well described, but few studies have considered the relationship between them. Objective: The purpose of this study was, therefore, to investigate the interrelationships between markers of aging in different parts of the body. Methods: A cross-sectional study design was used. Structural and functional markers of aging were measured in a number of different body systems. Results: Conditional independence analysis demonstrated that the aging markers selected clustered into two groups, either related to chronological age or adult height. Visual acuity, lens opacity, hearing threshold, cognitive decline, and the number of teeth were associated with age, while systolic blood pressure and skin thickness were related to height. Grip strength was associated with both. Conclusions: The differential associations of the aging markers with chronological age and adult height suggest that different systems do not age together. This may have relevance for understanding what underlies aging, and these preliminary findings now require replication in other aging cohorts.
83-86
Aihie Sayer, A.
fb4c2053-6d51-4fc1-9489-c3cb431b0ffb
Osmond, C.
2677bf85-494f-4a78-adf8-580e1b8acb81
Briggs, R.
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
1999
Aihie Sayer, A.
fb4c2053-6d51-4fc1-9489-c3cb431b0ffb
Osmond, C.
2677bf85-494f-4a78-adf8-580e1b8acb81
Briggs, R.
a6b65ef0-e90c-4c07-bf5b-b70130c128b3
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Aihie Sayer, A., Osmond, C., Briggs, R. and Cooper, C.
(1999)
Do all systems age together?
Gerontology, 45 (2), .
(doi:10.1159/000022068).
Abstract
Background: Aging changes in different body system are well described, but few studies have considered the relationship between them. Objective: The purpose of this study was, therefore, to investigate the interrelationships between markers of aging in different parts of the body. Methods: A cross-sectional study design was used. Structural and functional markers of aging were measured in a number of different body systems. Results: Conditional independence analysis demonstrated that the aging markers selected clustered into two groups, either related to chronological age or adult height. Visual acuity, lens opacity, hearing threshold, cognitive decline, and the number of teeth were associated with age, while systolic blood pressure and skin thickness were related to height. Grip strength was associated with both. Conclusions: The differential associations of the aging markers with chronological age and adult height suggest that different systems do not age together. This may have relevance for understanding what underlies aging, and these preliminary findings now require replication in other aging cohorts.
This record has no associated files available for download.
More information
Published date: 1999
Identifiers
Local EPrints ID: 159719
URI: http://eprints.soton.ac.uk/id/eprint/159719
ISSN: 0304-324X
PURE UUID: 3e7776a3-11b5-4dbc-8786-fff1d98d08cf
Catalogue record
Date deposited: 07 Jul 2010 14:20
Last modified: 18 Mar 2024 02:45
Export record
Altmetrics
Contributors
Author:
A. Aihie Sayer
Author:
R. Briggs
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
