Programmed assembly of peptide-functionalized gold nanoparticles on DNA templates
Programmed assembly of peptide-functionalized gold nanoparticles on DNA templates
 
  We present a novel nanoparticle building block system based on the interactions between short synthetic oligonucleotides and peptides. Gold nanoparticles coated with DNA-binding peptides can be attached to self-organized oligonucleotide templates to formulate well-ordered structures of nanoparticles. By regulating the amount of DNA-binding peptide attached to the nanoparticle surface and using specifically designed oligonucleotides, the nanoparticle assembly can be controlled to form dimers, trimers, and adjustable-length nanoparticle chains as well as more complex structures.
  
  
  13760-13762
  
    
      Coomber, Danielle
      
        9f633247-884f-48a2-abfb-1f82e9f435c9
      
     
  
    
      Bartczak, Dorota
      
        4d706d11-ee17-4e30-9ba8-1d4b3d878f71
      
     
  
    
      Gerrard, Simon R.
      
        4ed7b304-42c2-497a-b00d-5ac8a1bedd24
      
     
  
    
      Tyas, Sarah
      
        3162c2b4-53e2-44e5-8304-69d9556d5999
      
     
  
    
      Kanaras, Antonios G.
      
        667ecfdc-7647-4bd8-be03-a47bf32504c7
      
     
  
    
      Stulz, Eugen
      
        9a6c04cf-32ca-442b-9281-bbf3d23c622d
      
     
  
  
   
  
  
    
    
  
    
      7 September 2010
    
    
  
  
    
      Coomber, Danielle
      
        9f633247-884f-48a2-abfb-1f82e9f435c9
      
     
  
    
      Bartczak, Dorota
      
        4d706d11-ee17-4e30-9ba8-1d4b3d878f71
      
     
  
    
      Gerrard, Simon R.
      
        4ed7b304-42c2-497a-b00d-5ac8a1bedd24
      
     
  
    
      Tyas, Sarah
      
        3162c2b4-53e2-44e5-8304-69d9556d5999
      
     
  
    
      Kanaras, Antonios G.
      
        667ecfdc-7647-4bd8-be03-a47bf32504c7
      
     
  
    
      Stulz, Eugen
      
        9a6c04cf-32ca-442b-9281-bbf3d23c622d
      
     
  
       
    
 
  
    
      
  
  
  
  
  
  
    Coomber, Danielle, Bartczak, Dorota, Gerrard, Simon R., Tyas, Sarah, Kanaras, Antonios G. and Stulz, Eugen
  
  
  
  
   
    (2010)
  
  
    
    Programmed assembly of peptide-functionalized gold nanoparticles on DNA templates.
  
  
  
  
    Langmuir, 26 (17), .
  
   (doi:10.1021/la1023554). 
  
  
  
    (PMID:20672816)
   
  
  
  
  
  
   
  
    
      
        
          Abstract
          We present a novel nanoparticle building block system based on the interactions between short synthetic oligonucleotides and peptides. Gold nanoparticles coated with DNA-binding peptides can be attached to self-organized oligonucleotide templates to formulate well-ordered structures of nanoparticles. By regulating the amount of DNA-binding peptide attached to the nanoparticle surface and using specifically designed oligonucleotides, the nanoparticle assembly can be controlled to form dimers, trimers, and adjustable-length nanoparticle chains as well as more complex structures.
        
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  More information
  
    
      e-pub ahead of print date: 30 July 2010
 
    
      Published date: 7 September 2010
 
    
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
     
        Organisations:
        Organic Chemistry: SCF
      
    
  
    
  
  
  
    
  
    
  
  
        Identifiers
        Local EPrints ID: 162523
        URI: http://eprints.soton.ac.uk/id/eprint/162523
        
          
        
        
        
          ISSN: 0743-7463
        
        
          PURE UUID: 23ad3f79-ba99-4c75-80de-71cd4d2b2c6b
        
  
    
        
          
        
    
        
          
        
    
        
          
            
          
        
    
        
          
        
    
        
          
            
              
            
          
        
    
        
          
            
              
            
          
        
    
  
  Catalogue record
  Date deposited: 23 Aug 2010 15:22
  Last modified: 14 Mar 2024 02:53
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      Contributors
      
          
          Author:
          
            
            
              Danielle Coomber
            
          
        
      
          
          Author:
          
            
            
              Dorota Bartczak
            
          
        
      
          
          Author:
          
            
              
              
                Simon R. Gerrard
              
              
            
            
          
        
      
          
          Author:
          
            
            
              Sarah Tyas
            
          
        
      
        
      
        
      
      
      
    
  
   
  
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