Dissolution characteristics of extrusion freeformed hydroxyapatite-tricalcium phosphate scaffolds
Dissolution characteristics of extrusion freeformed hydroxyapatite-tricalcium phosphate scaffolds
The dissolution behaviour of calcium phosphate filaments made by extrusion freeforming for hard tissue scaffolds was measured. The solubility of filaments with different HA/?-TCP ratios sintered at temperatures from 1,100 to 1,300°C was measured under simulated physiological conditions (tris buffer solution: tris(hydroxyl) methyl–aminomethane–HCl), pH 7.4, 37°C). Calcium and phosphate concentrations were measured separately by inductively coupled plasma (ICP) atomic emission spectroscopy. Surface morphologies and composition before and after immersion were analyzed by SEM and EDS. The results clearly show that as the ?-TCP content increased, the dissolution increased. Higher sintering temperatures, with consequent closure of surface pores, resulted in lower dissolution. Examination of the surface suggested dissolution on preferred sites by pitting.
3345-3353
Yang, H.Y.
2becc2d6-1748-4eba-b907-69e006e81d91
Thompson, I.
2707fa6a-3614-4fe6-b55a-a29d87d37f3d
Yang, S.F.
e0018adf-8123-4a54-b8dd-306c10ca48f1
Chi, X.P.
b6611614-ea7b-443c-a251-061c5a34c470
Evans, J.R.G.
6f6c8a4c-24ac-4144-a555-51438e4d40e0
Cook, R.J.
fb9ca464-c20e-446c-8379-5a79b5a8dd96
November 2008
Yang, H.Y.
2becc2d6-1748-4eba-b907-69e006e81d91
Thompson, I.
2707fa6a-3614-4fe6-b55a-a29d87d37f3d
Yang, S.F.
e0018adf-8123-4a54-b8dd-306c10ca48f1
Chi, X.P.
b6611614-ea7b-443c-a251-061c5a34c470
Evans, J.R.G.
6f6c8a4c-24ac-4144-a555-51438e4d40e0
Cook, R.J.
fb9ca464-c20e-446c-8379-5a79b5a8dd96
Yang, H.Y., Thompson, I., Yang, S.F., Chi, X.P., Evans, J.R.G. and Cook, R.J.
(2008)
Dissolution characteristics of extrusion freeformed hydroxyapatite-tricalcium phosphate scaffolds.
Journal of Materials Science: Materials in Medicine, 19 (11), .
(doi:10.1007/s10856-008-3473-7).
(PMID:18545944)
Abstract
The dissolution behaviour of calcium phosphate filaments made by extrusion freeforming for hard tissue scaffolds was measured. The solubility of filaments with different HA/?-TCP ratios sintered at temperatures from 1,100 to 1,300°C was measured under simulated physiological conditions (tris buffer solution: tris(hydroxyl) methyl–aminomethane–HCl), pH 7.4, 37°C). Calcium and phosphate concentrations were measured separately by inductively coupled plasma (ICP) atomic emission spectroscopy. Surface morphologies and composition before and after immersion were analyzed by SEM and EDS. The results clearly show that as the ?-TCP content increased, the dissolution increased. Higher sintering temperatures, with consequent closure of surface pores, resulted in lower dissolution. Examination of the surface suggested dissolution on preferred sites by pitting.
This record has no associated files available for download.
More information
Published date: November 2008
Organisations:
Engineering Mats & Surface Engineerg Gp
Identifiers
Local EPrints ID: 165027
URI: http://eprints.soton.ac.uk/id/eprint/165027
ISSN: 0957-4530
PURE UUID: fe487b2a-f2fa-4424-b232-6e048930518d
Catalogue record
Date deposited: 07 Oct 2010 14:42
Last modified: 14 Mar 2024 02:09
Export record
Altmetrics
Contributors
Author:
H.Y. Yang
Author:
I. Thompson
Author:
X.P. Chi
Author:
J.R.G. Evans
Author:
R.J. Cook
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
