The University of Southampton
University of Southampton Institutional Repository

Anatomical distribution of synovitis in knee osteoarthritis and its association with joint effusion assessed on non-enhanced and contrast-enhanced MRI

Record type: Article

Purpose: To describe the anatomical distribution of synovitis and its association with joint effusion on non-enhanced and contrast-enhanced (CE) MRI in patients with knee osteoarthritis (OA).

Methods: Baseline MRI was performed at 1.5 T using axial proton density (PD)-weighted (w) fat suppressed (fs) and axial and sagittal T1-w fs CE sequences. Synovial enhancement was scored in nine articular subregions. Maximum synovial enhancement was grouped as absent (0), equivocal (1) and definite (2 and 3). Effusion was scored from 0 to 3 on the axial sequences. We described the anatomical distribution of synovitis, its association with effusion and compared assessment of effusion on T1-w fs CE and PD fs sequences.

Results: 111 subjects were included and examined by MRI. 89.2% of knees exhibited at least one subregion with a minimum grade 2 and 39.6% at the maximum of a grade 3. The commonest sites for definite synovitis were posterior to the posterior cruciate ligament (PCL) in 71.2% and in the suprapatellar region in 59.5% of all knees. On T1-w fs CE, 73.0% of knees showed any effusion. Definite synovitis in at least one location was present in 96.3% knees with an effusion and in 70.0% without an effusion. Higher grades of effusion were scored on the PD fs sequence.

Conclusion: Definite synovitis was present in the majority of knees with or without effusion with the commonest sites being posterior to the PCL and in the suprapatellar recess. Joint effusion as measured on PD fs images does not only represent effusion but also synovial thickening.

Full text not available from this repository.

Citation

Roemer, F.W., Javaid, M. Kassim, Guermazi, A., Thomas, M., Kiran, A., Keen, R., King, L. and Arden, N.K. (2010) Anatomical distribution of synovitis in knee osteoarthritis and its association with joint effusion assessed on non-enhanced and contrast-enhanced MRI Osteoarthritis and Cartilage, 18, (10), pp. 1269-1274. (doi:10.1016/j.joca.2010.07.008). (PMID:20691796).

More information

Published date: October 2010
Keywords: osteoarthritis, knee, mri, gadolinium, effusion, synovitis, distribution

Identifiers

Local EPrints ID: 165261
URI: http://eprints.soton.ac.uk/id/eprint/165261
ISSN: 1063-4584
PURE UUID: 3a0bb4eb-ed2a-44d7-8438-3a48c29caf0f

Catalogue record

Date deposited: 11 Oct 2010 08:39
Last modified: 18 Jul 2017 12:27

Export record

Altmetrics

Contributors

Author: F.W. Roemer
Author: M. Kassim Javaid
Author: A. Guermazi
Author: M. Thomas
Author: A. Kiran
Author: R. Keen
Author: L. King
Author: N.K. Arden

University divisions


Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×