Anatomical distribution of synovitis in knee osteoarthritis and its association with joint effusion assessed on non-enhanced and contrast-enhanced MRI
Anatomical distribution of synovitis in knee osteoarthritis and its association with joint effusion assessed on non-enhanced and contrast-enhanced MRI
Purpose: To describe the anatomical distribution of synovitis and its association with joint effusion on non-enhanced and contrast-enhanced (CE) MRI in patients with knee osteoarthritis (OA).
Methods: Baseline MRI was performed at 1.5 T using axial proton density (PD)-weighted (w) fat suppressed (fs) and axial and sagittal T1-w fs CE sequences. Synovial enhancement was scored in nine articular subregions. Maximum synovial enhancement was grouped as absent (0), equivocal (1) and definite (2 and 3). Effusion was scored from 0 to 3 on the axial sequences. We described the anatomical distribution of synovitis, its association with effusion and compared assessment of effusion on T1-w fs CE and PD fs sequences.
Results: 111 subjects were included and examined by MRI. 89.2% of knees exhibited at least one subregion with a minimum grade 2 and 39.6% at the maximum of a grade 3. The commonest sites for definite synovitis were posterior to the posterior cruciate ligament (PCL) in 71.2% and in the suprapatellar region in 59.5% of all knees. On T1-w fs CE, 73.0% of knees showed any effusion. Definite synovitis in at least one location was present in 96.3% knees with an effusion and in 70.0% without an effusion. Higher grades of effusion were scored on the PD fs sequence.
Conclusion: Definite synovitis was present in the majority of knees with or without effusion with the commonest sites being posterior to the PCL and in the suprapatellar recess. Joint effusion as measured on PD fs images does not only represent effusion but also synovial thickening.
osteoarthritis, knee, mri, gadolinium, effusion, synovitis, distribution
1269-1274
Roemer, F.W.
8044ed78-19c1-4411-a651-16017a1b78f0
Javaid, M. Kassim
64155236-2ef0-4065-b684-cf723a888117
Guermazi, A.
b2164f06-6621-449a-8319-eeff0ce9d0ad
Thomas, M.
f5239f6a-49f5-4645-9f1c-37ae8fbcd0d5
Kiran, A.
5c4f2210-4951-4226-a44b-e6ecfb9c5c71
Keen, R.
510d049d-5c13-4448-acbd-0f2f3b5f2a64
King, L.
ca67081e-4a76-4438-b430-81d324d53307
Arden, N.K.
23af958d-835c-4d79-be54-4bbe4c68077f
October 2010
Roemer, F.W.
8044ed78-19c1-4411-a651-16017a1b78f0
Javaid, M. Kassim
64155236-2ef0-4065-b684-cf723a888117
Guermazi, A.
b2164f06-6621-449a-8319-eeff0ce9d0ad
Thomas, M.
f5239f6a-49f5-4645-9f1c-37ae8fbcd0d5
Kiran, A.
5c4f2210-4951-4226-a44b-e6ecfb9c5c71
Keen, R.
510d049d-5c13-4448-acbd-0f2f3b5f2a64
King, L.
ca67081e-4a76-4438-b430-81d324d53307
Arden, N.K.
23af958d-835c-4d79-be54-4bbe4c68077f
Roemer, F.W., Javaid, M. Kassim, Guermazi, A., Thomas, M., Kiran, A., Keen, R., King, L. and Arden, N.K.
(2010)
Anatomical distribution of synovitis in knee osteoarthritis and its association with joint effusion assessed on non-enhanced and contrast-enhanced MRI.
Osteoarthritis and Cartilage, 18 (10), .
(doi:10.1016/j.joca.2010.07.008).
(PMID:20691796)
Abstract
Purpose: To describe the anatomical distribution of synovitis and its association with joint effusion on non-enhanced and contrast-enhanced (CE) MRI in patients with knee osteoarthritis (OA).
Methods: Baseline MRI was performed at 1.5 T using axial proton density (PD)-weighted (w) fat suppressed (fs) and axial and sagittal T1-w fs CE sequences. Synovial enhancement was scored in nine articular subregions. Maximum synovial enhancement was grouped as absent (0), equivocal (1) and definite (2 and 3). Effusion was scored from 0 to 3 on the axial sequences. We described the anatomical distribution of synovitis, its association with effusion and compared assessment of effusion on T1-w fs CE and PD fs sequences.
Results: 111 subjects were included and examined by MRI. 89.2% of knees exhibited at least one subregion with a minimum grade 2 and 39.6% at the maximum of a grade 3. The commonest sites for definite synovitis were posterior to the posterior cruciate ligament (PCL) in 71.2% and in the suprapatellar region in 59.5% of all knees. On T1-w fs CE, 73.0% of knees showed any effusion. Definite synovitis in at least one location was present in 96.3% knees with an effusion and in 70.0% without an effusion. Higher grades of effusion were scored on the PD fs sequence.
Conclusion: Definite synovitis was present in the majority of knees with or without effusion with the commonest sites being posterior to the PCL and in the suprapatellar recess. Joint effusion as measured on PD fs images does not only represent effusion but also synovial thickening.
This record has no associated files available for download.
More information
Published date: October 2010
Keywords:
osteoarthritis, knee, mri, gadolinium, effusion, synovitis, distribution
Identifiers
Local EPrints ID: 165261
URI: http://eprints.soton.ac.uk/id/eprint/165261
ISSN: 1063-4584
PURE UUID: 3a0bb4eb-ed2a-44d7-8438-3a48c29caf0f
Catalogue record
Date deposited: 11 Oct 2010 08:39
Last modified: 14 Mar 2024 02:10
Export record
Altmetrics
Contributors
Author:
F.W. Roemer
Author:
M. Kassim Javaid
Author:
A. Guermazi
Author:
M. Thomas
Author:
A. Kiran
Author:
R. Keen
Author:
L. King
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics