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Percutaneous medical liver core biopsies: correlation between tissue length and the number of portal tracts

Percutaneous medical liver core biopsies: correlation between tissue length and the number of portal tracts
Percutaneous medical liver core biopsies: correlation between tissue length and the number of portal tracts
Objective Liver biopsy is an important tool for the diagnosis and assessment of liver disease. The authors aimed to establish the relationship between biopsy length and the number of total portal tracts.

Methods The authors reviewed 163 16G percutaneous medical liver biopsies taken at a tertiary referral centre over a 14-month period. Haematoxylin and eosin sections were analysed using imaging software and portal tracts were counted.

Results Liver biopsy length correlates with total portal tracts. The median biopsy length was 13.3 mm with a median of six portal tracts. Ninety-five per cent of biopsies measuring at least 15 mm contained six portal tracts or more with a significant difference between total portal tracts when compared with biopsies <15 mm (p<0.0001).

Conclusion To facilitate adequate histological assessment by examining at least six portal tracts, the authors suggest that 16G biopsies should be at least 15 mm long.
0021-9746
655-656
Chan, James
2d501ded-7d51-41f5-a65b-215a9c11768d
Alwahab, Yasir
4f7cef24-36de-44e9-a7c3-2ce7d00d0df5
Tilley, Charles
79c8321c-a61c-4c2c-b74f-9bcb213b1181
Carr, Norman
810e44dc-90d5-496c-85b6-6b2fa1c07dd7
Chan, James
2d501ded-7d51-41f5-a65b-215a9c11768d
Alwahab, Yasir
4f7cef24-36de-44e9-a7c3-2ce7d00d0df5
Tilley, Charles
79c8321c-a61c-4c2c-b74f-9bcb213b1181
Carr, Norman
810e44dc-90d5-496c-85b6-6b2fa1c07dd7

Chan, James, Alwahab, Yasir, Tilley, Charles and Carr, Norman (2010) Percutaneous medical liver core biopsies: correlation between tissue length and the number of portal tracts. Journal of Clinical Pathology, 63 (7), 655-656. (doi:10.1136/jcp.2010.076273). (PMID:20501453)

Record type: Article

Abstract

Objective Liver biopsy is an important tool for the diagnosis and assessment of liver disease. The authors aimed to establish the relationship between biopsy length and the number of total portal tracts.

Methods The authors reviewed 163 16G percutaneous medical liver biopsies taken at a tertiary referral centre over a 14-month period. Haematoxylin and eosin sections were analysed using imaging software and portal tracts were counted.

Results Liver biopsy length correlates with total portal tracts. The median biopsy length was 13.3 mm with a median of six portal tracts. Ninety-five per cent of biopsies measuring at least 15 mm contained six portal tracts or more with a significant difference between total portal tracts when compared with biopsies <15 mm (p<0.0001).

Conclusion To facilitate adequate histological assessment by examining at least six portal tracts, the authors suggest that 16G biopsies should be at least 15 mm long.

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More information

Published date: 24 May 2010

Identifiers

Local EPrints ID: 169093
URI: https://eprints.soton.ac.uk/id/eprint/169093
ISSN: 0021-9746
PURE UUID: 8498a657-ef22-4072-9b98-cf6f113e94c5

Catalogue record

Date deposited: 09 Dec 2010 14:01
Last modified: 16 Jul 2019 23:49

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