Capretto, Lorenzo, Cheng, Wei, Carugo, Dario, Hill, Martyn and Zhang, Xunli
Microfluidic reactors for controlled synthesis of polymeric micelles
[in special issue: 11th European Sumposium on Controlled Drug Delivery]
Journal of Controlled Release, 148, (1), . (doi:10.1016/j.jconrel.2010.07.037).
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This study outlines the relationship between polymer concentration, flow rate ratio and microreactor dimension and the size of polymeric micelles produced in continuous flow microreactors. The general production strategy is based on a nanoprecipitation process within the microfluidic environment which improves control, reproducibility, and homogeneity of the size of the produced polymeric micelles.
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