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Process optimization for the production of alginate microparticles containing wjmscs by a design of experiments (doe) approach

Mazzitelli, S., Capretto, L., Zhang, X.L., Penolazzi, L., Lambertini, E., Piva, R. and Nastruzzi, C. (2010) Process optimization for the production of alginate microparticles containing wjmscs by a design of experiments (doe) approach [in special issue: 11th European Sumposium on Controlled Drug Delivery] Journal of Controlled Release, 148, (1), e76-e77. (doi:10.1016/j.jconrel.2010.07.014).

Record type: Article

Abstract


The paper describes (a) the isolation and characterization of Wharton's Jelly Mesenchymal Stem cells (WJMSCs), (b) the encapsulation of WJMSCs in alginate microbeads by an encapsulation device based on a vibrating-nozzle, (c) the optimization of the procedure for the encapsulation of WJMSCs by a Design of Experiment (DoE) approach, and (d) the evaluation of viability, proliferation and osteoblastic differentiation of the encapsulated WJMSCs.

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Published date: 2010

Identifiers

Local EPrints ID: 172309
URI: http://eprints.soton.ac.uk/id/eprint/172309
ISSN: 0168-3659
PURE UUID: ea3d1fb6-9bea-48d7-a5ca-7a7d8a33fd37

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Date deposited: 25 Jan 2011 11:52
Last modified: 18 Jul 2017 12:14

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Contributors

Author: S. Mazzitelli
Author: L. Capretto
Author: X.L. Zhang
Author: L. Penolazzi
Author: E. Lambertini
Author: R. Piva
Author: C. Nastruzzi

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