The University of Southampton
University of Southampton Institutional Repository

Identification of a TAP-independent, immunoproteasome-dependent CD8+ T-cell epitope in Epstein-Barr virus latent membrane protein 2

Lautscham, Georg, Haigh, Tracey, Mayrhofer, Sabine, Taylor, Graham, Croom-Carter, Debbie, Leese, Alison, Gadola, Stephan, Cerundolo, Vincenzo, Rickinson, Alan and Blake, Neil (2003) Identification of a TAP-independent, immunoproteasome-dependent CD8+ T-cell epitope in Epstein-Barr virus latent membrane protein 2 Journal of Virology, 77, (4), pp. 2757-2761. (doi:10.1128/JVI.77.4.2757-2761.2003). (PMID:12552018).

Record type: Article

Abstract

We have identified an HLA-A2-restricted CD8+ T-cell epitope, FLYALALLL, in the Epstein-Barr virus (EBV) latent membrane protein 2 (LMP2), an important target antigen in the context of EBV-associated malignancies. This epitope is TAP independent, like other hydrophobic LMP2-derived epitopes, but uniquely is dependent upon the immunoproteasome for its generation.

Full text not available from this repository.

More information

Published date: February 2003

Identifiers

Local EPrints ID: 175469
URI: http://eprints.soton.ac.uk/id/eprint/175469
ISSN: 0022-538X
PURE UUID: ef56bbcf-4cdd-43fc-8f78-9bd9ea4a0af1

Catalogue record

Date deposited: 23 Feb 2011 15:25
Last modified: 18 Jul 2017 12:09

Export record

Altmetrics

Contributors

Author: Georg Lautscham
Author: Tracey Haigh
Author: Sabine Mayrhofer
Author: Graham Taylor
Author: Debbie Croom-Carter
Author: Alison Leese
Author: Stephan Gadola
Author: Vincenzo Cerundolo
Author: Alan Rickinson
Author: Neil Blake

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×