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Disseminated intravascular coagulation and purpura fulminans secondary to infection

Faust, S.N., Heyderman, R.S. and Levin, M. (2000) Disseminated intravascular coagulation and purpura fulminans secondary to infection Best Practice & Research: Clinical Haematology, 13, (2), pp. 179-197. (doi:10.1053/beha.2000.0067). (PMID:10942620).

Record type: Article

Abstract

Infection is one of the commonest causes of disseminated intravascular coagulation (DIC). DIC is a complex disorder that results from an imbalance of the pro- and anticoagulant regulatory pathways. This chapter will explain the cellular and molecular basis of the disorder and consider the rationale behind current and experimental treatment strategies.

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More information

Published date: June 2000
Keywords: disseminated intravascular coagulation (dic), purpura fulminans, pathophysiology, therapy, clinical trials, gram-negative, meningococcal, tissue factor (tf), tissue factor pathway inhibitor (tfpi), antithrombin (atiii), thrombomodulin (tm), protein c (pc)/activated protein c (apc), tissue plasminogen activator (tpa)

Identifiers

Local EPrints ID: 175585
URI: http://eprints.soton.ac.uk/id/eprint/175585
ISSN: 1532-1924
PURE UUID: 182ed328-2ac7-413f-9f5b-19ae27a8e7a7
ORCID for S.N. Faust: ORCID iD orcid.org/0000-0003-3410-7642

Catalogue record

Date deposited: 24 Feb 2011 15:12
Last modified: 11 Jul 2017 09:51

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Contributors

Author: S.N. Faust ORCID iD
Author: R.S. Heyderman
Author: M. Levin

University divisions

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