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Microdynamics and criticality of adaptive regulatory networks

Microdynamics and criticality of adaptive regulatory networks
Microdynamics and criticality of adaptive regulatory networks
We present a model of adaptive regulatory networks consisting of a simple biologically motivated rewiring procedure coupled to an elementary stability criterion. The resulting networks exhibit a characteristic stationary heavy-tailed degree distribution, show complex structural microdynamics, and self-organize to a dynamically critical state. We show analytically that the observed criticality results from the formation and breaking of transient feedback loops during the adaptive process
168701-[4pp]
MacArthur, Ben D.
2c0476e7-5d3e-4064-81bb-104e8e88bb6b
Sanchez-Garcia, Ruben
8246cea2-ae1c-44f2-94e9-bacc9371c3ed
Ma’ayan, Avi
49ea105e-cb86-4d59-8655-5456e240dc7e
MacArthur, Ben D.
2c0476e7-5d3e-4064-81bb-104e8e88bb6b
Sanchez-Garcia, Ruben
8246cea2-ae1c-44f2-94e9-bacc9371c3ed
Ma’ayan, Avi
49ea105e-cb86-4d59-8655-5456e240dc7e

MacArthur, Ben D., Sanchez-Garcia, Ruben and Ma’ayan, Avi (2010) Microdynamics and criticality of adaptive regulatory networks. Physical Review Letters, 104 (16), 168701-[4pp]. (doi:10.1103/PhysRevLett.104.168701). (PMID:20482087)

Record type: Article

Abstract

We present a model of adaptive regulatory networks consisting of a simple biologically motivated rewiring procedure coupled to an elementary stability criterion. The resulting networks exhibit a characteristic stationary heavy-tailed degree distribution, show complex structural microdynamics, and self-organize to a dynamically critical state. We show analytically that the observed criticality results from the formation and breaking of transient feedback loops during the adaptive process

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Published date: April 2010
Organisations: Medicine, Mathematics
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Identifiers

Local EPrints ID: 175697
URI: http://eprints.soton.ac.uk/id/eprint/175697
DOI: doi:10.1103/PhysRevLett.104.168701
PURE UUID: 58249235-4d15-4e90-813e-fb1dd252b7b5
ORCID for Ben D. MacArthur: ORCID iD orcid.org/0000-0002-5396-9750
ORCID for Ruben Sanchez-Garcia: ORCID iD orcid.org/0000-0001-6479-3028

Catalogue record

Date deposited: 25 Feb 2011 14:58
Last modified: 14 Mar 2024 02:56

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Contributors

Author: Ben D. MacArthur ORCID iD
Author: Ruben Sanchez-Garcia ORCID iD
Author: Avi Ma’ayan

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