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Multistep DNA-templated reactions for the synthesis of functional sequence controlled oligomers

Multistep DNA-templated reactions for the synthesis of functional sequence controlled oligomers
Multistep DNA-templated reactions for the synthesis of functional sequence controlled oligomers
Biomimetic: A strand displacement mechanism was designed to permit DNA-templated synthesis of functional oligomers of arbitrary length (see scheme). Key features of the mechanism are that successive coupling reactions take place in near-identical environments and that purification is only necessary in the last synthesis step.

biomimetic synthesis, dna, oligomers, template synthesis, wittig reaction
1433-7851
7948-7951
McKee, Mireya L.
189d4b60-90b1-4e2f-b95e-2c534bc89087
Milnes, Phillip J.
fcb9cc31-266f-477a-ab39-a32793470c0a
Bath, Jonathan
fc276b69-5e06-43e9-a3d5-d7324bc23267
Stulz, Eugen
9a6c04cf-32ca-442b-9281-bbf3d23c622d
Turberfield, Andrew J.
e12469b0-4ae6-44a5-9099-e9273ab803d4
O'Reilly, Rachel K.
086bc91e-2303-4543-b79c-ae16ada0b101
McKee, Mireya L.
189d4b60-90b1-4e2f-b95e-2c534bc89087
Milnes, Phillip J.
fcb9cc31-266f-477a-ab39-a32793470c0a
Bath, Jonathan
fc276b69-5e06-43e9-a3d5-d7324bc23267
Stulz, Eugen
9a6c04cf-32ca-442b-9281-bbf3d23c622d
Turberfield, Andrew J.
e12469b0-4ae6-44a5-9099-e9273ab803d4
O'Reilly, Rachel K.
086bc91e-2303-4543-b79c-ae16ada0b101

McKee, Mireya L., Milnes, Phillip J., Bath, Jonathan, Stulz, Eugen, Turberfield, Andrew J. and O'Reilly, Rachel K. (2010) Multistep DNA-templated reactions for the synthesis of functional sequence controlled oligomers. Angewandte Chemie International Edition, 49 (43), 7948-7951. (doi:10.1002/anie.201002721).

Record type: Article

Abstract

Biomimetic: A strand displacement mechanism was designed to permit DNA-templated synthesis of functional oligomers of arbitrary length (see scheme). Key features of the mechanism are that successive coupling reactions take place in near-identical environments and that purification is only necessary in the last synthesis step.

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More information

Published date: 18 October 2010
Keywords: biomimetic synthesis, dna, oligomers, template synthesis, wittig reaction
Organisations: Chemistry

Identifiers

Local EPrints ID: 176843
URI: http://eprints.soton.ac.uk/id/eprint/176843
ISSN: 1433-7851
PURE UUID: 089ebd07-964a-4cd4-b05a-dd167bdbb39f
ORCID for Eugen Stulz: ORCID iD orcid.org/0000-0002-5302-2276

Catalogue record

Date deposited: 11 Mar 2011 11:56
Last modified: 17 Dec 2019 01:45

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