The kinetics of bulk hydration of the disaccharides α-lactose and trehalose by in situ neutron powder diffraction
The kinetics of bulk hydration of the disaccharides α-lactose and trehalose by in situ neutron powder diffraction
The hydrations of the excipients stable α-lactose (Lαs), with two particle sizes, and trehalose have been studied by neutron powder diffraction; analysis of the Avrami plots, derived from the bulk polycrystalline phase compositions, allows elucidation of the kinetics and mechanisms involved in these hydration processes.
345-348
Ting, Valeska P.
72559b76-c835-43eb-97e2-28f4b69e219c
Schmidtmann, Marc
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Henry, Paul F.
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Dann, Sandie E.
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Crisp, Jenna L.
8c9b605a-54e4-478a-b0d2-cb6a34348788
Wilson, Chick C.
4b5044d0-fb05-4d70-92b1-d12387c593a1
Weller, Mark T.
5be42713-fd58-4dc6-bc7a-86a801e201bc
2010
Ting, Valeska P.
72559b76-c835-43eb-97e2-28f4b69e219c
Schmidtmann, Marc
a4fdd057-e08c-4b13-bc5d-a41181e8e17f
Henry, Paul F.
6ab0d6ca-bb2c-4286-9fad-1a5894dd8b75
Dann, Sandie E.
05f6d118-2661-431c-bf40-c414f96a24bc
Crisp, Jenna L.
8c9b605a-54e4-478a-b0d2-cb6a34348788
Wilson, Chick C.
4b5044d0-fb05-4d70-92b1-d12387c593a1
Weller, Mark T.
5be42713-fd58-4dc6-bc7a-86a801e201bc
Ting, Valeska P., Schmidtmann, Marc, Henry, Paul F., Dann, Sandie E., Crisp, Jenna L., Wilson, Chick C. and Weller, Mark T.
(2010)
The kinetics of bulk hydration of the disaccharides α-lactose and trehalose by in situ neutron powder diffraction.
MedChemComm, 1 (5), .
(doi:10.1039/c0md00093k).
Abstract
The hydrations of the excipients stable α-lactose (Lαs), with two particle sizes, and trehalose have been studied by neutron powder diffraction; analysis of the Avrami plots, derived from the bulk polycrystalline phase compositions, allows elucidation of the kinetics and mechanisms involved in these hydration processes.
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Published date: 2010
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Local EPrints ID: 176939
URI: http://eprints.soton.ac.uk/id/eprint/176939
ISSN: 2040-2503
PURE UUID: 2cdd64ba-0804-40a8-8302-9bffee813bf1
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Date deposited: 14 Mar 2011 09:44
Last modified: 14 Mar 2024 02:41
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Contributors
Author:
Valeska P. Ting
Author:
Marc Schmidtmann
Author:
Paul F. Henry
Author:
Sandie E. Dann
Author:
Jenna L. Crisp
Author:
Chick C. Wilson
Author:
Mark T. Weller
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