Detection of serum reverse transcriptase activity in patients with ALS and unaffected blood relatives
Detection of serum reverse transcriptase activity in patients with ALS and unaffected blood relatives
These results confirm that patients with ALS have a significantly higher prevalence of serum reverse transcriptase (RT) activity than that seen in unrelated control subjects. The finding of a similarly increased prevalence in blood relatives of ALS patients raises the possibility that the observed RT activity might be due to an inherited endogenous retrovirus.
454-458
Steele, A.J.
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Al-Chalabi, A.
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Ferrante, K.
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Cudkowicz, M.E.
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Brown, R.H.
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Garson, J. A.
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8 February 2005
Steele, A.J.
cfbcbf3f-30f2-45f2-a5f7-d22555745d78
Al-Chalabi, A.
db16bbda-7684-49b4-9b2d-9799c7dba33c
Ferrante, K.
1e0d520a-0e67-4ac2-8568-c943b2577420
Cudkowicz, M.E.
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Brown, R.H.
e24ddb95-c19b-4bf7-bf4a-6fc393602e80
Garson, J. A.
4c2dbab0-9830-4657-aa5c-eae1487fc685
Steele, A.J., Al-Chalabi, A., Ferrante, K., Cudkowicz, M.E., Brown, R.H. and Garson, J. A.
(2005)
Detection of serum reverse transcriptase activity in patients with ALS and unaffected blood relatives.
Neurology, 64 (3), .
(doi:10.1212/01.WNL.0000150899.76130.71).
Abstract
These results confirm that patients with ALS have a significantly higher prevalence of serum reverse transcriptase (RT) activity than that seen in unrelated control subjects. The finding of a similarly increased prevalence in blood relatives of ALS patients raises the possibility that the observed RT activity might be due to an inherited endogenous retrovirus.
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Published date: 8 February 2005
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Local EPrints ID: 178131
URI: http://eprints.soton.ac.uk/id/eprint/178131
ISSN: 0028-3878
PURE UUID: 3ff535ab-6c2d-48a3-86a0-88d30649861b
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Date deposited: 23 Mar 2011 09:25
Last modified: 14 Mar 2024 02:45
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Contributors
Author:
A.J. Steele
Author:
A. Al-Chalabi
Author:
K. Ferrante
Author:
M.E. Cudkowicz
Author:
R.H. Brown
Author:
J. A. Garson
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