The University of Southampton
University of Southampton Institutional Repository

The use of quantitative ultrasound to diagnose osteoporosis in patients with rheumatoid arthritis

The use of quantitative ultrasound to diagnose osteoporosis in patients with rheumatoid arthritis
The use of quantitative ultrasound to diagnose osteoporosis in patients with rheumatoid arthritis
Background: Patients with rheumatoid arthritis (RA) are recognised as being at risk of osteoporosis both as part of the disease process and due to the drugs used to treat it.1,2 This study aimed to consider the use of calcaneal scanning using quantitative ultrasound - Contact Ultrasound Bone Analysis (CUBA) to demonstrate osteoporosis in patients with RA.
Methods: Forty-six patients (35 female,11 male) with establised RA had a DEXA scan of the non-dominant wrist and a CUBA scan of the non-dominant heel. Sensitivity, specificity, positive and negative predictive values were used to determine the correlation between osteoporosis as determined by the CUBA heel scan compared to a DEXA wrist scan.
Results: The CUBA heel scan revealed a sensitivity of 90% with a specificty of 44% for osteoporosis compared to a DEXA scan of the wrist. The positive predictive value of the CUBA was 31% and the negative predictive value was 94%.
If a normal bone density is achieved with the CUBA there is a 94% certainty this is correct. However, if osteoporosis is demonstrated using CUBA there is only a 31% certainty this is correct. In such instances a secondary scan utilising a different methodology e.g. DEXA would needed. Future work should consider the effect of minor alterations to the equipment and/or scanning protocol in order to yield greater accuracy.
Conclusions: The clinical implications of this work are that the CUBA unit could be used as a primary screening device.Given some of the cost and accessibilty issues associated with DEXA scans, quantitative ultrasound may have a role in screening for osteoporosis in the Primary Care setting.
rheumatoid, rheumatoid arthritis, arthritis
1462-0324
ii151 - ii152
Cryer, J. R.
0999fbd4-8bb8-4fc2-a82d-2135c3aa5cfd
Otter, S. J.
a0c24032-58a1-4b69-b6c7-2ef91c6aae5d
Bowen, Catherine Jane
0e86ee01-6155-4e17-b8af-a2a0684676b2
Cryer, J. R.
0999fbd4-8bb8-4fc2-a82d-2135c3aa5cfd
Otter, S. J.
a0c24032-58a1-4b69-b6c7-2ef91c6aae5d
Bowen, Catherine Jane
0e86ee01-6155-4e17-b8af-a2a0684676b2

Cryer, J. R., Otter, S. J. and Bowen, Catherine Jane (2004) The use of quantitative ultrasound to diagnose osteoporosis in patients with rheumatoid arthritis. Rheumatology, 43 (Supplement 2), ii151 - ii152.

Record type: Article

Abstract

Background: Patients with rheumatoid arthritis (RA) are recognised as being at risk of osteoporosis both as part of the disease process and due to the drugs used to treat it.1,2 This study aimed to consider the use of calcaneal scanning using quantitative ultrasound - Contact Ultrasound Bone Analysis (CUBA) to demonstrate osteoporosis in patients with RA.
Methods: Forty-six patients (35 female,11 male) with establised RA had a DEXA scan of the non-dominant wrist and a CUBA scan of the non-dominant heel. Sensitivity, specificity, positive and negative predictive values were used to determine the correlation between osteoporosis as determined by the CUBA heel scan compared to a DEXA wrist scan.
Results: The CUBA heel scan revealed a sensitivity of 90% with a specificty of 44% for osteoporosis compared to a DEXA scan of the wrist. The positive predictive value of the CUBA was 31% and the negative predictive value was 94%.
If a normal bone density is achieved with the CUBA there is a 94% certainty this is correct. However, if osteoporosis is demonstrated using CUBA there is only a 31% certainty this is correct. In such instances a secondary scan utilising a different methodology e.g. DEXA would needed. Future work should consider the effect of minor alterations to the equipment and/or scanning protocol in order to yield greater accuracy.
Conclusions: The clinical implications of this work are that the CUBA unit could be used as a primary screening device.Given some of the cost and accessibilty issues associated with DEXA scans, quantitative ultrasound may have a role in screening for osteoporosis in the Primary Care setting.

Full text not available from this repository.

More information

Published date: 2004
Additional Information: Poster 401 from British Society for Rheumatology Annual Meeting 2004
Keywords: rheumatoid, rheumatoid arthritis, arthritis

Identifiers

Local EPrints ID: 17864
URI: https://eprints.soton.ac.uk/id/eprint/17864
ISSN: 1462-0324
PURE UUID: c7891cd3-12e9-4cb2-90cf-16c11eda5b4f

Catalogue record

Date deposited: 26 May 2006
Last modified: 17 Jul 2017 16:37

Export record

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×