The University of Southampton
University of Southampton Institutional Repository

Nanomolar detection with high sensitivity microfluidic absorption cells manufactured in tinted PMMA for chemical analysis

Floquet, Cedric F.A., Sieben, Vincent J., Milani, Ambra, Joly, E, Ogilvie, Iain R.G., Morgan, Hywel and Mowlem, Matthew C. (2011) Nanomolar detection with high sensitivity microfluidic absorption cells manufactured in tinted PMMA for chemical analysis Talanta, 84, (1), pp. 235-239.

Record type: Article

Abstract

We describe a novel, cost effective and simple technique for the manufacture of high sensitivity absorption cells for microfluidic analytical systems. The cells are made from tinted polymethyl methacrylate (PMMA) in which microfluidic channels are fabricated. Two windows (typically 250 ?m thick, resulting in little optical power loss) are formed at either end of the channel through which light is coupled. Unwanted stray light from the emitter passes through a greater thickness of the tinted substrate (typically the length of the cell) and is preferentially absorbed. In effect, this creates a pin-hole configuration over the length of the absorption cell, providing improved performances (sensitivity, S/N ratios, baseline noise and limit of detection) when used as an absorption cell compared to clear substrates. The method is used to achieve a LOD of 20 nM with a colourimetric iron assay and a LOD of 0.22 milli-absorption units with a pH assay.

Full text not available from this repository.

More information

Published date: 1 March 2011
Keywords: Microfluidic, PMMA, Colourimetric assays, Absorption, Microsensors
Organisations: Ocean Technology and Engineering

Identifiers

Local EPrints ID: 179503
URI: http://eprints.soton.ac.uk/id/eprint/179503
ISSN: 0039-9140
PURE UUID: f22e6db8-b595-44b1-a1bd-969d9f764953
ORCID for Hywel Morgan: ORCID iD orcid.org/0000-0003-4850-5676

Catalogue record

Date deposited: 01 Apr 2011 13:01
Last modified: 17 Oct 2017 11:22

Export record

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×