The University of Southampton
University of Southampton Institutional Repository

The CHD challenge: comparing four cost-effectivess models

Turner, David, Raftery, James, Cooper, Keith, Fairbank, Eleanor, Palmer, Stephen, Ward, Sue and Ara, Roberta (2011) The CHD challenge: comparing four cost-effectivess models Value in Health, 14, (1), pp. 53-60. (doi:10.1016/j.jval.2010.10.009).

Record type: Article

Abstract

Objectives: to compare four UK models evaluating the cost-effectiveness of interventions in coronary heart disease (CHD), exploring the relative importance of structure and inputs in accounting for differences, and the scope for consensus on structure and data.

Methods: we compared published cost-effectiveness results (incremental cost, quality-adjusted life year, and cost-effectiveness ratio) of three models conforming to the National Institute for Health and Clinical Excellence guidelines dealing with three interventions (statins, percutaneous coronary intervention, and clopidogrel) with a model developed in Southampton. Comparisons were made using three separate stages: 1) comparison of published results; 2) comparison of the results using the same data inputs wherever possible; and 3) an in-depth exploration of reasons for differences and the potential for consensus.

Results: although published results differed by up to 73% (for statins), standardization of inputs (stage 2) narrowed these gaps. Greater understanding of the reasons for differences was achieved, but a consensus on preferred values for all data inputs was not reached.

Conclusions: we found that published guidance on methods was important to reduce variation in important model inputs. Although the comparison of models did not lead to consensus for all model inputs, it provided a better understanding of the reasons for these differences, and enhanced the transparency and credibility of all models. Similar comparisons would be aided by fuller publication of models, perhaps through detailed web appendices

Full text not available from this repository.

More information

Published date: January 2011
Organisations: Primary Care & Population Sciences

Identifiers

Local EPrints ID: 181291
URI: http://eprints.soton.ac.uk/id/eprint/181291
ISSN: 1098-3015
PURE UUID: 0537e314-36ea-4840-b876-ae378f4e36db

Catalogue record

Date deposited: 14 Apr 2011 09:08
Last modified: 18 Jul 2017 11:59

Export record

Altmetrics

Contributors

Author: David Turner
Author: James Raftery
Author: Keith Cooper
Author: Eleanor Fairbank
Author: Stephen Palmer
Author: Sue Ward
Author: Roberta Ara

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×