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European Surveillance of Antimicrobial Consumption (ESAC): disease-specific quality indicators for outpatient antibiotic prescribing

European Surveillance of Antimicrobial Consumption (ESAC): disease-specific quality indicators for outpatient antibiotic prescribing
European Surveillance of Antimicrobial Consumption (ESAC): disease-specific quality indicators for outpatient antibiotic prescribing
Background

In 2007, ESAC (http://www.esac.ua.ac.be) published a set of 12 valid drug-specific quality indicators for outpatient antibiotic use in Europe. In this study, the authors aimed to develop evidence-based disease-specific quality indicators for outpatient antibiotic prescribing in Europe.

Methods

Two meetings were convened to produce a list of disease-specific quality indicators for outpatient antibiotic prescribing which conform to internationally agreed recommendations, building on a similar development of drug-specific quality indicators, and in collaboration with CHAMP and HAPPY AUDIT. 62 experts were asked to complete two scoring rounds of the proposed indicators on seven dimensions: their relevance to (1) reducing antimicrobial resistance, (2) patient health benefit, (3) cost-effectiveness, (4) policy makers, (5) individual prescribers, (6) their evidence base and (7) their range of acceptable use, using a scale ranging from 1 (=completely disagree) to 9 (=completely agree). Scores were judged according to the UCLA-RAND appropriateness method.

Results

For the six main indications for antibiotic prescribing (acute otitis media, acute upper-respiratory infection, acute/chronic sinusitis, acute tonsillitis, acute bronchitis/bronchiolitis, cystitis/other urinary infection) and for pneumonia, three quality indicators were proposed, the percentage prescribed (a) antibiotics; (b) recommended antibiotics; (c) quinolones. This set was scored by 40 experts from 25 countries. After one scoring round, all indicators were already rated as relevant on all dimensions, except one.

Conclusion

All proposed disease-specific quality indicators for outpatient antibiotic prescribing have face validity and are potentially applicable. They could be used to better describe antibiotic use and assess the quality of antibiotic prescribing patterns in ambulatory care.
2044-5415
764-772
Adriaenssens, Niels
329eff77-09cc-4387-b054-06d79e3b0fa6
Coenen, Samuel
3d0dc4e0-e5ba-4d66-ba92-15900ccc551e
Tonkin-Crine, Sarah
65679835-9bdc-48b6-92f3-cc6322cccc4f
Verheij, Theo J.M.
817a26b8-7db9-4e79-b00e-c0457f19f236
Little, Paul
1bf2d1f7-200c-47a5-ab16-fe5a8756a777
Goossens, Herman
31f8e1ae-7da0-473c-bd49-f911c2187451
on behalf of the ESAC Project Group
Adriaenssens, Niels
329eff77-09cc-4387-b054-06d79e3b0fa6
Coenen, Samuel
3d0dc4e0-e5ba-4d66-ba92-15900ccc551e
Tonkin-Crine, Sarah
65679835-9bdc-48b6-92f3-cc6322cccc4f
Verheij, Theo J.M.
817a26b8-7db9-4e79-b00e-c0457f19f236
Little, Paul
1bf2d1f7-200c-47a5-ab16-fe5a8756a777
Goossens, Herman
31f8e1ae-7da0-473c-bd49-f911c2187451

Adriaenssens, Niels, Coenen, Samuel, Tonkin-Crine, Sarah, Verheij, Theo J.M., Little, Paul and Goossens, Herman , on behalf of the ESAC Project Group (2011) European Surveillance of Antimicrobial Consumption (ESAC): disease-specific quality indicators for outpatient antibiotic prescribing. BMJ Quality and Safety, 20, 764-772. (doi:10.1136/bmjqs.2010.049049). (PMID:21441602)

Record type: Article

Abstract

Background

In 2007, ESAC (http://www.esac.ua.ac.be) published a set of 12 valid drug-specific quality indicators for outpatient antibiotic use in Europe. In this study, the authors aimed to develop evidence-based disease-specific quality indicators for outpatient antibiotic prescribing in Europe.

Methods

Two meetings were convened to produce a list of disease-specific quality indicators for outpatient antibiotic prescribing which conform to internationally agreed recommendations, building on a similar development of drug-specific quality indicators, and in collaboration with CHAMP and HAPPY AUDIT. 62 experts were asked to complete two scoring rounds of the proposed indicators on seven dimensions: their relevance to (1) reducing antimicrobial resistance, (2) patient health benefit, (3) cost-effectiveness, (4) policy makers, (5) individual prescribers, (6) their evidence base and (7) their range of acceptable use, using a scale ranging from 1 (=completely disagree) to 9 (=completely agree). Scores were judged according to the UCLA-RAND appropriateness method.

Results

For the six main indications for antibiotic prescribing (acute otitis media, acute upper-respiratory infection, acute/chronic sinusitis, acute tonsillitis, acute bronchitis/bronchiolitis, cystitis/other urinary infection) and for pneumonia, three quality indicators were proposed, the percentage prescribed (a) antibiotics; (b) recommended antibiotics; (c) quinolones. This set was scored by 40 experts from 25 countries. After one scoring round, all indicators were already rated as relevant on all dimensions, except one.

Conclusion

All proposed disease-specific quality indicators for outpatient antibiotic prescribing have face validity and are potentially applicable. They could be used to better describe antibiotic use and assess the quality of antibiotic prescribing patterns in ambulatory care.

Text
BMJ Qual Saf-2011-Adriaenssens-bmjqs.2010.049049.pdf - Accepted Manuscript
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More information

Accepted/In Press date: 5 February 2011
Published date: 21 March 2011
Organisations: Primary Care & Population Sciences

Identifiers

Local EPrints ID: 181311
URI: https://eprints.soton.ac.uk/id/eprint/181311
ISSN: 2044-5415
PURE UUID: 5b4b5706-8a8a-4b2c-8154-81019500e3d3

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Date deposited: 14 Apr 2011 10:16
Last modified: 01 Dec 2017 17:34

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