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Filaggrin null mutations associate with increased frequencies of allergen-specific CD4+ T-helper 2 cells in patients with atopic eczema

Record type: Article

These data would support a model where barrier dysfunction possibly promotes greater allergen penetration and delivery to drive allergen-specific CD4+ T cells. This could further contribute to respiratory and cutaneous inflammatory disease.

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Citation

McPherson, T., Sherman, V. J., Aslam, A., Crack, L., Chan, H., Lloyd-Lavery, A., Jones, L.E., Ardern-Jones, M and Ogg, G. (2010) Filaggrin null mutations associate with increased frequencies of allergen-specific CD4+ T-helper 2 cells in patients with atopic eczema British Journal of Dermatology, 163, (3), pp. 544-549. (doi:10.1111/j.1365-2133.2010.09866.x). (PMID:20500796).

More information

Published date: September 2010

Identifiers

Local EPrints ID: 181625
URI: http://eprints.soton.ac.uk/id/eprint/181625
ISSN: 0007-0963
PURE UUID: ecd7dbdb-9f54-47d7-a55b-05d7be134cb4

Catalogue record

Date deposited: 15 Apr 2011 11:12
Last modified: 18 Jul 2017 11:58

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Contributors

Author: T. McPherson
Author: V. J. Sherman
Author: A. Aslam
Author: L. Crack
Author: H. Chan
Author: A. Lloyd-Lavery
Author: L.E. Jones
Author: M Ardern-Jones
Author: G. Ogg

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