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Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology

Hammiche, Fatima, Vujkovic, Marijana, Wilburg, Willeke, de Vries, Jeanne H.M., Macklon, Nick S., Laven, Joop S.E. and Steegers-Theunissen, Régine P.M. (2011) Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology Fertility and Sterility, 95, (5), pp. 1820-1823. (doi:10.1016/j.fertnstert.2010.11.021). (PMID:21130435).

Record type: Article


The association between preconception dietary intake of the polyunsaturated fatty acids (LC-PUFAs) omega-6 and omega-3 and the E(2) levels and IVF/intracytoplasmic sperm injection (ICSI) outcome were investigated in women in a prospective study. It revealed that high intakes of omega-3 LC-PUFA alpha-linolenic acid increase baseline E(2), high intakes of eicosapentaenoic acid and docosahexaenoic acid reduce E(2) response and the number of follicles after ovarian stimulation, and total omega-3 intake, in particular alpha-linolenic acid and docosahexaenoic acid, improve embryo morphology.

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Published date: April 2011
Keywords: nutrition, assisted reproduction, fertility outcome


Local EPrints ID: 185235
ISSN: 0015-0282
PURE UUID: 9b211b63-504b-4f3f-8285-0bf91d109de1

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Date deposited: 10 May 2011 08:37
Last modified: 18 Jul 2017 11:49

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Author: Fatima Hammiche
Author: Marijana Vujkovic
Author: Willeke Wilburg
Author: Jeanne H.M. de Vries
Author: Nick S. Macklon
Author: Joop S.E. Laven
Author: Régine P.M. Steegers-Theunissen

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