Dynamics of the development of multiple follicles during ovarian stimulation for in vitro fertilization using recombinant follicle-stimulating hormone (Puregon) and various doses of the gonadotropin-releasing hormone antagonist ganirelix (Orgalutran/Antagon)
Dynamics of the development of multiple follicles during ovarian stimulation for in vitro fertilization using recombinant follicle-stimulating hormone (Puregon) and various doses of the gonadotropin-releasing hormone antagonist ganirelix (Orgalutran/Antagon)
Follicular growth was unaffected by the dose of GnRH antagonist. A rise in follicular phase FSH serum concentrations during the follicular phase, largely related to exogenous FSH, enabled ongoing follicular growth in all treatment groups. The effect of GnRH antagonist on late follicular phase E(2) levels could not be exclusively attributed to suppression of LH.
follicle development, fsh, gnrh antagonist, ganirelix, two-gonadotropin two-cell concept, estradiol, androstenedione, lh, total follicular surface area, ivf
688-693
de Jong, Diederick
377712dd-686d-45f6-b110-d5313f56e9b2
Macklon, Nicholas S.
7db1f4fc-a9f6-431f-a1f2-297bb8c9fb7e
Eijkemans, Marinus J.C.
f95640f3-5107-4b1b-b924-ebac8a334321
Mannaerts, Bernadette M.J.L.
905bd58c-1f35-4a27-8b59-bd4a557e87af
Coelingh Bennink, Herjan J.T.
18ef068f-8c70-4ee5-87d8-d15f50008125
Fauser, Bart C.J.M.
0edf5e0f-12db-4ca9-bf9c-00e85b7f4a3e
April 2001
de Jong, Diederick
377712dd-686d-45f6-b110-d5313f56e9b2
Macklon, Nicholas S.
7db1f4fc-a9f6-431f-a1f2-297bb8c9fb7e
Eijkemans, Marinus J.C.
f95640f3-5107-4b1b-b924-ebac8a334321
Mannaerts, Bernadette M.J.L.
905bd58c-1f35-4a27-8b59-bd4a557e87af
Coelingh Bennink, Herjan J.T.
18ef068f-8c70-4ee5-87d8-d15f50008125
Fauser, Bart C.J.M.
0edf5e0f-12db-4ca9-bf9c-00e85b7f4a3e
de Jong, Diederick, Macklon, Nicholas S., Eijkemans, Marinus J.C., Mannaerts, Bernadette M.J.L., Coelingh Bennink, Herjan J.T. and Fauser, Bart C.J.M.
(2001)
Dynamics of the development of multiple follicles during ovarian stimulation for in vitro fertilization using recombinant follicle-stimulating hormone (Puregon) and various doses of the gonadotropin-releasing hormone antagonist ganirelix (Orgalutran/Antagon).
Fertility and Sterility, 75 (4), .
(doi:10.1016/S0015-0282(00)01789-1).
(PMID:12057752)
Abstract
Follicular growth was unaffected by the dose of GnRH antagonist. A rise in follicular phase FSH serum concentrations during the follicular phase, largely related to exogenous FSH, enabled ongoing follicular growth in all treatment groups. The effect of GnRH antagonist on late follicular phase E(2) levels could not be exclusively attributed to suppression of LH.
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Published date: April 2001
Keywords:
follicle development, fsh, gnrh antagonist, ganirelix, two-gonadotropin two-cell concept, estradiol, androstenedione, lh, total follicular surface area, ivf
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Local EPrints ID: 185679
URI: http://eprints.soton.ac.uk/id/eprint/185679
ISSN: 0015-0282
PURE UUID: 0a85b920-8a91-499b-bdaf-ebabbe23b1ab
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Date deposited: 19 May 2011 08:27
Last modified: 14 Mar 2024 03:15
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Contributors
Author:
Diederick de Jong
Author:
Nicholas S. Macklon
Author:
Marinus J.C. Eijkemans
Author:
Bernadette M.J.L. Mannaerts
Author:
Herjan J.T. Coelingh Bennink
Author:
Bart C.J.M. Fauser
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