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Dynamics of the development of multiple follicles during ovarian stimulation for in vitro fertilization using recombinant follicle-stimulating hormone (Puregon) and various doses of the gonadotropin-releasing hormone antagonist ganirelix (Orgalutran/Antagon)

de Jong, Diederick, Macklon, Nicholas S., Eijkemans, Marinus J.C., Mannaerts, Bernadette M.J.L., Coelingh Bennink, Herjan J.T. and Fauser, Bart C.J.M. (2001) Dynamics of the development of multiple follicles during ovarian stimulation for in vitro fertilization using recombinant follicle-stimulating hormone (Puregon) and various doses of the gonadotropin-releasing hormone antagonist ganirelix (Orgalutran/Antagon) Fertility and Sterility, 75, (4), pp. 688-693. (doi:10.1016/S0015-0282(00)01789-1). (PMID:12057752).

Record type: Article

Abstract

Follicular growth was unaffected by the dose of GnRH antagonist. A rise in follicular phase FSH serum concentrations during the follicular phase, largely related to exogenous FSH, enabled ongoing follicular growth in all treatment groups. The effect of GnRH antagonist on late follicular phase E(2) levels could not be exclusively attributed to suppression of LH.

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Published date: April 2001
Keywords: follicle development, fsh, gnrh antagonist, ganirelix, two-gonadotropin two-cell concept, estradiol, androstenedione, lh, total follicular surface area, ivf

Identifiers

Local EPrints ID: 185679
URI: http://eprints.soton.ac.uk/id/eprint/185679
ISSN: 0015-0282
PURE UUID: 0a85b920-8a91-499b-bdaf-ebabbe23b1ab

Catalogue record

Date deposited: 19 May 2011 08:27
Last modified: 18 Jul 2017 11:48

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Contributors

Author: Diederick de Jong
Author: Marinus J.C. Eijkemans
Author: Bernadette M.J.L. Mannaerts
Author: Herjan J.T. Coelingh Bennink
Author: Bart C.J.M. Fauser

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