de Jong, Diederick, Macklon, Nicholas S., Eijkemans, Marinus J.C., Mannaerts, Bernadette M.J.L., Coelingh Bennink, Herjan J.T. and Fauser, Bart C.J.M.
Dynamics of the development of multiple follicles during ovarian stimulation for in vitro fertilization using recombinant follicle-stimulating hormone (Puregon) and various doses of the gonadotropin-releasing hormone antagonist ganirelix (Orgalutran/Antagon)
Fertility and Sterility, 75, (4), . (doi:10.1016/S0015-0282(00)01789-1). (PMID:12057752).
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Follicular growth was unaffected by the dose of GnRH antagonist. A rise in follicular phase FSH serum concentrations during the follicular phase, largely related to exogenous FSH, enabled ongoing follicular growth in all treatment groups. The effect of GnRH antagonist on late follicular phase E(2) levels could not be exclusively attributed to suppression of LH.
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