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Measuring the adherence to medication of elderly patients with heart failure: is there a gold standard?

Smith, Helen, Hankins, Matthew, Hodson, Andrew and George, Charles (2010) Measuring the adherence to medication of elderly patients with heart failure: is there a gold standard? International Journal of Cardiology, 145, (1), pp. 122-123. (doi:10.1016/j.ijcard.2009.06.025). (PMID:19615767).

Record type: Article


ACE inhibitors and loop diuretics are treatments of first choice for heart failure, but patients must take their medications regularly to achieve maximum benefit. Adherence is commonly assessed using pill counts, self-report or electronic monitoring, with the latter widely considered the ‘gold standard’. We assessed the concordance of these three methods in a sample of 52 elderly patients with heart failure over a six-week period. Substantial differences in adherence were found between the three methods. Adherence by self-report was very high for both ACE-I and diuretic, with little between-person variation. This was, however, uncorroborated by pill count and electronic monitoring. Closer examination of the electronic record suggested that the mean level of adherence overlooked patterns of openings more consistent with adherent behaviour. There seems to be no gold standard for measurement of adherence in this population.

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Published date: 5 November 2010
Keywords: heart failure, adherence, compliance


Local EPrints ID: 187309
ISSN: 0167-5273
PURE UUID: 5101cb8a-a02d-4262-8dcf-f1ab00f2abce

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Date deposited: 17 May 2011 12:34
Last modified: 18 Jul 2017 11:45

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Author: Helen Smith
Author: Matthew Hankins
Author: Andrew Hodson
Author: Charles George

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