Management of anti-Rhesus-D antibodies in pregnancy: a review from 1994 to 1998

Cheong, Ying C., Goodrick, Jean, Kyle, Phillippa M. and Soothill, Peter (2001) Management of anti-Rhesus-D antibodies in pregnancy: a review from 1994 to 1998. Fetal Diagnosis and Therapy, 16 (5), 294-298. (doi:10.1159/000053931). (PMID:11509852)

Record type: Article

Abstract

Intravascular as opposed to intraperitoneal transfusions were found to be the main method of transfusion in the later years in this study, a finding which was expected with improved sonographic equipment. Apart from this, management and prognosis of anti-D red cell isoimmunisation in pregnancy have remained relatively stable since the 1980s. Amniocentesis was useful in the management of such pregnancies, especially as an initial procedure in the cases with a lower initial anti-D level. In this series 90% of the fetuses requiring blood transfusion, but were without hydrops, survived, whereas this was about 70%, if they had become hydropic (this latter figure was reduced by 2 hydropic deaths before 20 weeks' gestation in the same very severely affected woman).

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