Jivraj, S., Anstie, B., Cheong, Y.C., Fairlie, F.M., Laird, S.M. and Li, T.C.
Obstetric and neonatal outcome in women with a history of recurrent miscarriage: a cohort study
Human Reproduction, 16, (1), . (doi:10.1093/humrep/16.1.102). (PMID:11139545).
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Obstetric and neonatal outcomes of women who had a history of recurrent miscarriage were compared with a control population from 1 January 1992 to 30 June 1998. Amongst a total of 162 pregnancies which progressed beyond 24 weeks gestation in women with a history of recurrent miscarriage, there were four perinatal deaths and 16 babies were admitted to the special care baby unit. The rates of preterm delivery (13%), small-for-gestational-age (13%), perinatal loss (2.5%) and Caesarean section (36%) were significantly (P < 0.05) higher than those of the control group (3.9, 2.1, 1 and 16.7% respectively). The ratio of male to female babies was equal. There was no significant difference in the incidence of hypertension or diabetes between the two groups. Patients with recurrent miscarriage represent a population at high risk of obstetric problems and close surveillance in the antenatal period is therefore required.
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