The University of Southampton
University of Southampton Institutional Repository

A thiyl radical mediated cascade sequence for the co-cyclisation of 1,6-hexadienes with sulfur atom transfer

Record type: Article

The paper describes a method for effecting the co-cyclisation of 1,6-dienes with concomitant sulfur atom transfer. The key step is a cascade reaction involving the addition of a thiyl radical to an alkene, cyclisation through a chair-like transition state and termination by homolytic substitution at sulfur. It has been used to synthesise a broad range of fused thiabicyclo[3.3.0]octanes.

Full text not available from this repository.

Citation

Harrowven, D. C., Hannam, J. C., Lucas, M. C., Newman, N. A. and Howes, P. D. (2000) A thiyl radical mediated cascade sequence for the co-cyclisation of 1,6-hexadienes with sulfur atom transfer Tetrahedron Letters, 41, (48), pp. 9345-9349. (doi:10.1016/S0040-4039(00)01701-9).

More information

Published date: 25 November 2000
Keywords: cyclisations, photochemistry, radicals and radical reactions, sulfur heterocycleshomolytic substitution, cyclization reactions, condensed thiophenes, lactam synthesis, disulfide, dienylamides, system

Identifiers

Local EPrints ID: 18853
URI: http://eprints.soton.ac.uk/id/eprint/18853
ISSN: 0040-4039
PURE UUID: 9de3f847-1231-4652-9587-51106783cd87

Catalogue record

Date deposited: 15 Dec 2005
Last modified: 17 Jul 2017 16:34

Export record

Altmetrics

Contributors

Author: D. C. Harrowven
Author: J. C. Hannam
Author: M. C. Lucas
Author: N. A. Newman
Author: P. D. Howes

University divisions


Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×