The University of Southampton
University of Southampton Institutional Repository

Synthesis of trifluoromethylpyrroles and related heterocycles from 4-ethyloxy-1,1,1-trifluorobut-3-ene-2-one

Andrew, R. J. and Mellor, J. M. (2000) Synthesis of trifluoromethylpyrroles and related heterocycles from 4-ethyloxy-1,1,1-trifluorobut-3-ene-2-one Tetrahedron, 56, (37), pp. 7267-7272. (doi:10.1016/S0040-4020(00)00598-6).

Record type: Article

Abstract

Syntheses cf intermediate 4-dialkylamino-1,1,1-trifluorobut-3-ene-2-ones are described from 4-ethyloxy-1,1,1-trifluorobut-3-ene-2-one and alpha-aminoacids. In subsequent cyclisations pyrroles and other bicyclic heteroaromatics having trifluoromethyl substitution are obtained either by simple dehydration or with concomitant decarboxylation.

Full text not available from this repository.

More information

Published date: 8 September 2000
Keywords: amino acids, pyrroles, thiaproline, trifluoromethyl haloacetylated enol ethers, fluorine-containing 1, 2-dihydropyrimidines, structural determination, nitrogen-heterocycles, efficient synthesis, magnetic-resonance, facile synthesis, convenient, cyclization, ketones

Identifiers

Local EPrints ID: 18865
URI: http://eprints.soton.ac.uk/id/eprint/18865
ISSN: 0040-4020
PURE UUID: c7d9bd8c-f50a-46e8-b5cf-f34ff9482279

Catalogue record

Date deposited: 16 Dec 2005
Last modified: 17 Jul 2017 16:34

Export record

Altmetrics

Contributors

Author: R. J. Andrew
Author: J. M. Mellor

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×