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Solid-phase synthesis of cyclic sulfonamides employing a ring-closing metathesis-cleavage strategy

Brown, R. C. D., Castro, J. L. and Moriggi, J. D. (2000) Solid-phase synthesis of cyclic sulfonamides employing a ring-closing metathesis-cleavage strategy Tetrahedron Letters, 41, (19), pp. 3681-3685. (doi:10.1016/S0040-4039(00)00442-1).

Record type: Article

Abstract

Ring-closing olefin metathesis using the Grubbs catalyst was applied to the cyclisative release of resin-bound sulfonamides. Flexible linkers apparently facilitated the cyclisation-leavage, allowing a number of novel cyclic sulfonamides to be prepared in good yields using catalytic amounts of the Grubbs catalyst.

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More information

Published date: 6 May 2000
Keywords: ring-closing metathesis, solid-phase synthesis, sulfonamides, linkers organic-synthesis, olefin metathesis, support, oligosaccharides, heterocycles, cyclization

Identifiers

Local EPrints ID: 18909
URI: http://eprints.soton.ac.uk/id/eprint/18909
ISSN: 0040-4039
PURE UUID: 64adae4b-dd7f-4e01-b17c-de2cb38df3e7

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Date deposited: 15 Dec 2005
Last modified: 17 Jul 2017 16:34

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Contributors

Author: R. C. D. Brown
Author: J. L. Castro
Author: J. D. Moriggi

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