Solid-phase synthesis of cyclic sulfonamides employing a ring-closing metathesis-cleavage strategy


Brown, R. C. D., Castro, J. L. and Moriggi, J. D. (2000) Solid-phase synthesis of cyclic sulfonamides employing a ring-closing metathesis-cleavage strategy Tetrahedron Letters, 41, (19), pp. 3681-3685. (doi:10.1016/S0040-4039(00)00442-1).

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Description/Abstract

Ring-closing olefin metathesis using the Grubbs catalyst was applied to the cyclisative release of resin-bound sulfonamides. Flexible linkers apparently facilitated the cyclisation-leavage, allowing a number of novel cyclic sulfonamides to be prepared in good yields using catalytic amounts of the Grubbs catalyst.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1016/S0040-4039(00)00442-1
ISSNs: 0040-4039 (print)
Keywords: ring-closing metathesis, solid-phase synthesis, sulfonamides, linkers organic-synthesis, olefin metathesis, support, oligosaccharides, heterocycles, cyclization
Subjects:
ePrint ID: 18909
Date :
Date Event
6 May 2000Published
Date Deposited: 15 Dec 2005
Last Modified: 16 Apr 2017 23:08
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/18909

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