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Solid-phase synthesis of aryl ethers on high loading dendrimer resin

Solid-phase synthesis of aryl ethers on high loading dendrimer resin
Solid-phase synthesis of aryl ethers on high loading dendrimer resin
Resin-bound dendrimers have the potential to increase bead loading by at least one order of magnitude. In this letter we report the solid-phase synthesis of a library of aryl ethers using high-loading dendrimer beads, and compare the synthetic efficiency with that of TentaGel (Polystyrene-PEG) resin.
dendrimers, solid-phase synthesis, high-loading beads, single-bead screeningmitsunobu reaction
0040-4039
3763-3767
Basso, A.
9cdcd616-ad0c-431a-b3f3-f39343a63694
Evans, B.
4c435ee0-5ec3-4369-a9fc-f649824f98eb
Pegg, N.
864f9e25-f82f-4220-8694-6f6c8f820dc5
Bradley, M.
078a34d6-96c4-4ce1-9aa1-454d9ee0030d
Basso, A.
9cdcd616-ad0c-431a-b3f3-f39343a63694
Evans, B.
4c435ee0-5ec3-4369-a9fc-f649824f98eb
Pegg, N.
864f9e25-f82f-4220-8694-6f6c8f820dc5
Bradley, M.
078a34d6-96c4-4ce1-9aa1-454d9ee0030d

Basso, A., Evans, B., Pegg, N. and Bradley, M. (2000) Solid-phase synthesis of aryl ethers on high loading dendrimer resin. Tetrahedron Letters, 41 (19), 3763-3767. (doi:10.1016/S0040-4039(00)00479-2).

Record type: Article

Abstract

Resin-bound dendrimers have the potential to increase bead loading by at least one order of magnitude. In this letter we report the solid-phase synthesis of a library of aryl ethers using high-loading dendrimer beads, and compare the synthetic efficiency with that of TentaGel (Polystyrene-PEG) resin.

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More information

Published date: 6 May 2000
Keywords: dendrimers, solid-phase synthesis, high-loading beads, single-bead screeningmitsunobu reaction

Identifiers

Local EPrints ID: 18910
URI: http://eprints.soton.ac.uk/id/eprint/18910
ISSN: 0040-4039
PURE UUID: e15a7aeb-ceeb-47a7-bf9b-4658b7ef6349

Catalogue record

Date deposited: 15 Dec 2005
Last modified: 15 Mar 2024 06:09

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Contributors

Author: A. Basso
Author: B. Evans
Author: N. Pegg
Author: M. Bradley

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