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Bilateral spastic cerebral palsy-MRI pathology and origin. Analysis from a representative series of 56 cases.

Bilateral spastic cerebral palsy-MRI pathology and origin. Analysis from a representative series of 56 cases.
Bilateral spastic cerebral palsy-MRI pathology and origin. Analysis from a representative series of 56 cases.
MRI of the brain was performed on 56 children with bilateral spastic cerebral palsy (CP) at a mean age of 10.7 years. Specific pathology was found in 91 per cent; periventricular leukomalacia was present in 42 per cent of term- and 87 per cent of preterm-born children. Parasagittal subcorticocortical injury, multicystic encephalomalacia and basal ganglia lesions were identified in 16 per cent, in all but one associated with severe peri-/neonatal events at term or near term. Maldevelopment comprised 9 per cent, all but one found in term-born children. MRI morphology correlated strikingly with outcome. Periventricular leukomalacia was associated with more severe disability in term- than preterm-born children.
1469-8749
379-397
Krägeloh-Mann, Ingeborg
aec979ce-1396-4720-8c09-962bee930fcd
Petersen, Dirk
d776bb55-1464-4183-9049-d336ffbea6e9
Hagberg, Gudrun
4fce860f-b4c9-4721-a4d0-8cfbe1ee00de
Hagberg, Bengt
00ca8667-9cc4-4ba5-972b-ae835018213a
Michaelis, Richard
6f5e8705-610d-496c-91b5-92659e1e2344
Krägeloh-Mann, Ingeborg
aec979ce-1396-4720-8c09-962bee930fcd
Petersen, Dirk
d776bb55-1464-4183-9049-d336ffbea6e9
Hagberg, Gudrun
4fce860f-b4c9-4721-a4d0-8cfbe1ee00de
Hagberg, Bengt
00ca8667-9cc4-4ba5-972b-ae835018213a
Michaelis, Richard
6f5e8705-610d-496c-91b5-92659e1e2344

Krägeloh-Mann, Ingeborg, Petersen, Dirk, Hagberg, Gudrun, Hagberg, Bengt and Michaelis, Richard (1995) Bilateral spastic cerebral palsy-MRI pathology and origin. Analysis from a representative series of 56 cases. Developmental Medicine and Child Neurology, 37 (5), 379-397. (doi:10.1111/j.1469-8749.1995.tb12022.x). (PMID:8566452)

Record type: Article

Abstract

MRI of the brain was performed on 56 children with bilateral spastic cerebral palsy (CP) at a mean age of 10.7 years. Specific pathology was found in 91 per cent; periventricular leukomalacia was present in 42 per cent of term- and 87 per cent of preterm-born children. Parasagittal subcorticocortical injury, multicystic encephalomalacia and basal ganglia lesions were identified in 16 per cent, in all but one associated with severe peri-/neonatal events at term or near term. Maldevelopment comprised 9 per cent, all but one found in term-born children. MRI morphology correlated strikingly with outcome. Periventricular leukomalacia was associated with more severe disability in term- than preterm-born children.

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Published date: May 1995
Organisations: Clinical Neurosciences

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Local EPrints ID: 189533
URI: http://eprints.soton.ac.uk/id/eprint/189533
ISSN: 1469-8749
PURE UUID: 45dc6030-e89a-4725-b32e-bae8d5a1ae8f

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Date deposited: 02 Jun 2011 15:27
Last modified: 21 Aug 2017 16:32

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