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Carbenoid insertion into alkenylzirconocenes - a convergent synthesis of functionalised allylmetallics

Carbenoid insertion into alkenylzirconocenes - a convergent synthesis of functionalised allylmetallics
Carbenoid insertion into alkenylzirconocenes - a convergent synthesis of functionalised allylmetallics
Insertion of lithium alkylcarbenoids RC(A)LiX, A= CN, P(O)(OEt)(2), SO2Ph, OMe into alkenylzirconocene chlorides derived by hydrozirconation of terminal alkynes affords functionalised allylzirconium reagents which may be further elaborated.
boronic esters, carbonyl-compounds, aldehydes, alpha, reagents, hydrozirconation, homologation, metals, regioselectivity, zirconacycles
0040-4039
6211-6216
Kasatkin, A. N.
63fa6751-0f10-447a-8419-6dc1a2a3e196
Whitby, R. J.
3b6b79e2-863d-4d31-a4f6-ebe786aabd79
Kasatkin, A. N.
63fa6751-0f10-447a-8419-6dc1a2a3e196
Whitby, R. J.
3b6b79e2-863d-4d31-a4f6-ebe786aabd79

Kasatkin, A. N. and Whitby, R. J. (2000) Carbenoid insertion into alkenylzirconocenes - a convergent synthesis of functionalised allylmetallics. Tetrahedron Letters, 41 (32), 6211-6216. (doi:10.1016/S0040-4039(00)01024-8).

Record type: Article

Abstract

Insertion of lithium alkylcarbenoids RC(A)LiX, A= CN, P(O)(OEt)(2), SO2Ph, OMe into alkenylzirconocene chlorides derived by hydrozirconation of terminal alkynes affords functionalised allylzirconium reagents which may be further elaborated.

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More information

Published date: 5 August 2000
Keywords: boronic esters, carbonyl-compounds, aldehydes, alpha, reagents, hydrozirconation, homologation, metals, regioselectivity, zirconacycles

Identifiers

Local EPrints ID: 19063
URI: http://eprints.soton.ac.uk/id/eprint/19063
ISSN: 0040-4039
PURE UUID: 61184e8e-f25f-4327-aef3-f67799f09043

Catalogue record

Date deposited: 15 Dec 2005
Last modified: 15 Mar 2024 06:10

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Contributors

Author: A. N. Kasatkin
Author: R. J. Whitby

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