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A clinical prediction rule for nerve function impairment in leprosy patients: revisited after 5 years of follow-up

Croft, R.P., Nicholls, P.G., Steyerberg, E.W., Richardus, J.H., Withington, S.G., Cairns, W. and Smith, S. (2003) A clinical prediction rule for nerve function impairment in leprosy patients: revisited after 5 years of follow-up Leprosy Review, 74, (1), pp. 35-41.

Record type: Article


Nerve function impairment (NFI) commonly occurs during or after chemotherapy in leprosy. We previously described a clinical predication rule to estimate the risk of NFI occurring within 2 years of diagnosis, based on 2510 patients who are followed up in the Bangladesh Acute Nerve Damage Study (BANDS). This prediction rule assigns new leprosy patients to one of three risk groups based on leprosy group and the presence or absence of NFI at registration. Updated data with up to 5 years of follow-up showed that 95% of all NFI occurred within 2 years. This study confirms the validity of the rule and supports the conclusion that there is little value for the detection of NFI in extending follow-up beyond 2 years.

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Published date: March 2003
Keywords: nfi, nerve function impairment, leprosy patients, clinical prediction rule, 5 year follow-up


Local EPrints ID: 19208
ISSN: 0305-7518
PURE UUID: 4de130f2-f2fa-4ca1-93f0-55f7d6a2d8bb

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Date deposited: 31 Jan 2006
Last modified: 17 Jul 2017 16:33

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Author: R.P. Croft
Author: P.G. Nicholls
Author: E.W. Steyerberg
Author: J.H. Richardus
Author: S.G. Withington
Author: W. Cairns
Author: S. Smith

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