Chemically resistant microfluidic valves from Viton® membranes bonded to COC and PMMA
Chemically resistant microfluidic valves from Viton® membranes bonded to COC and PMMA
We present a reliable technique for irreversibly bonding chemically inert Viton® membranes to PMMA and COC substrates to produce microfluidic devices with integrated elastomeric structures. Viton® is widely used in commercially available valves and has several advantages when compared to other elastomeric membranes currently utilised in microfluidic valves (e.g. PDMS), such as high solvent resistance, low porosity and high temperature tolerance. The bond strength was sufficient to withstand a fluid pressure of 400 kPa (PMMA/Viton®) and 310 kPa (COC/Viton®) before leakage or burst failure, which is sufficient for most microfluidic applications. We demonstrate and characterise on-chip pneumatic Viton® microvalves on PMMA and COC substrates. We also provide a detailed method for bonding fluorinated Viton® elastomer, a highly chemically compatible material, to PMMA and COC polymers. This allows the production of microfluidic devices able to handle a wide range of chemically harsh fluids and broadens the scope of the microfluidic platform concept.
2455-2459
Ogilvie, I.R.G.
fc08051a-1e06-4bb5-9d99-c93cf5e2e51d
Sieben, V.J.
402ed37e-1b54-425e-9b45-9e3d55902753
Cortese, B.
e404c24a-7fe7-4b70-b68f-48fcb7da9cba
Mowlem, M.C.
6f633ca2-298f-48ee-a025-ce52dd62124f
Morgan, H.
de00d59f-a5a2-48c4-a99a-1d5dd7854174
2011
Ogilvie, I.R.G.
fc08051a-1e06-4bb5-9d99-c93cf5e2e51d
Sieben, V.J.
402ed37e-1b54-425e-9b45-9e3d55902753
Cortese, B.
e404c24a-7fe7-4b70-b68f-48fcb7da9cba
Mowlem, M.C.
6f633ca2-298f-48ee-a025-ce52dd62124f
Morgan, H.
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Ogilvie, I.R.G., Sieben, V.J., Cortese, B., Mowlem, M.C. and Morgan, H.
(2011)
Chemically resistant microfluidic valves from Viton® membranes bonded to COC and PMMA.
Lab on a Chip, 11 (14), .
(doi:10.1039/c1lc20069k).
Abstract
We present a reliable technique for irreversibly bonding chemically inert Viton® membranes to PMMA and COC substrates to produce microfluidic devices with integrated elastomeric structures. Viton® is widely used in commercially available valves and has several advantages when compared to other elastomeric membranes currently utilised in microfluidic valves (e.g. PDMS), such as high solvent resistance, low porosity and high temperature tolerance. The bond strength was sufficient to withstand a fluid pressure of 400 kPa (PMMA/Viton®) and 310 kPa (COC/Viton®) before leakage or burst failure, which is sufficient for most microfluidic applications. We demonstrate and characterise on-chip pneumatic Viton® microvalves on PMMA and COC substrates. We also provide a detailed method for bonding fluorinated Viton® elastomer, a highly chemically compatible material, to PMMA and COC polymers. This allows the production of microfluidic devices able to handle a wide range of chemically harsh fluids and broadens the scope of the microfluidic platform concept.
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Published date: 2011
Organisations:
Ocean Technology and Engineering
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Local EPrints ID: 193801
URI: http://eprints.soton.ac.uk/id/eprint/193801
ISSN: 1473-0197
PURE UUID: 1bd6e457-5b90-4f38-ba67-7f19e56e24c1
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Date deposited: 20 Jul 2011 12:42
Last modified: 08 Jan 2022 02:59
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Author:
I.R.G. Ogilvie
Author:
V.J. Sieben
Author:
B. Cortese
Author:
M.C. Mowlem
Author:
H. Morgan
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