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Regional differences in treatment for osteoporosis: The global longitudinal study of osteoporosis in women(GLOW)

Diez-Perez, Adolfo, Hooven, Frederick H., Adachi, Jonathan D., Adami, Silvano, Anderson, Frederick A., Boonen, Steven, Chapurlat, Roland, Compston, Juliet E., Cooper, Cyrus, Delmas, Pierre, Greenspan, Susan L., Lacroix, Andrea Z., Lindsay, Robert, Netelenbos, J. Coen, Pfeilschifter, Johannes, Roux, Christian, Saag, Kenneth G., Sambrook, Philip, Silverman, Stuart, Siris, Ethel S., Watts, Nelson B., Nika, Grigor and Gehlbach, Stephen H. (2011) Regional differences in treatment for osteoporosis: The global longitudinal study of osteoporosis in women(GLOW) Bone, 49, (3), pp. 493-498. (doi:10.1016/j.bone.2011.05.007). (PMID:21605715).

Record type: Article


Among 58,009 women, current anti-osteoporosis medication use was lowest in Northern Europe (16%) and highest in USA and Australia (32%). Between 48% (USA, Southern Europe) and 68% (Northern Europe) of women aged ? 65 years with a history of spine or hip fracture since age 45 were untreated. Among women with osteoporosis, the percentage of treated cases was lowest in Europe (45–52% versus 62–65% elsewhere). Women with osteopenia and no other risk factors were treated with anti-osteoporosis medication most frequently in USA (31%) and Canada (31%), and least frequently in Southern Europe (12%), Northern Europe (13%), and Australia (16%). After adjusting for risk factors, US women were threefold as likely to be treated with anti-osteoporosis medication as Northern European women (odds ratio 2.8; 95% confidence interval 2.5–3.1) and 1.5 times as likely to be treated as Southern European women (1.5, 1.4–1.6). Up to half of women reporting previous hip or spine fracture did not receive treatment.

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Published date: 14 May 2011
Keywords: fracture, regional variation, women, risk factor, preventive treatment


Local EPrints ID: 194379
ISSN: 8756-3282
PURE UUID: 831f684a-b2af-479e-b183-ab528c0ac5e8
ORCID for Cyrus Cooper: ORCID iD

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Date deposited: 27 Jul 2011 13:52
Last modified: 18 Jul 2017 11:27

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Author: Adolfo Diez-Perez
Author: Frederick H. Hooven
Author: Jonathan D. Adachi
Author: Silvano Adami
Author: Frederick A. Anderson
Author: Steven Boonen
Author: Roland Chapurlat
Author: Juliet E. Compston
Author: Cyrus Cooper ORCID iD
Author: Pierre Delmas
Author: Susan L. Greenspan
Author: Andrea Z. Lacroix
Author: Robert Lindsay
Author: J. Coen Netelenbos
Author: Johannes Pfeilschifter
Author: Christian Roux
Author: Kenneth G. Saag
Author: Philip Sambrook
Author: Stuart Silverman
Author: Ethel S. Siris
Author: Nelson B. Watts
Author: Grigor Nika
Author: Stephen H. Gehlbach

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